… Taravella and Melissa A. Wilson Sayres have been added to the author list (associated with:
School of Life Sciences, Center for Evolution and Medicine, The Biodesign Institute, Arizona …

The human Y chromosome exhibits surprisingly low levels of genetic diversity. This could
result from neutral processes if the effective population size of males is reduced relative to …

Levels and patterns of genetic diversity can provide insights into a population’s history. In
species with sex chromosomes, differences between genomic regions with unique inheritance …

We report the sequences of 1,244 human Y chromosomes randomly ascertained from 26
worldwide populations by the 1000 Genomes Project. We discovered more than 65,000 …

The presence of fetal cells has been associated with both positive and negative effects on
maternal health. These paradoxical effects may be due to the fact that maternal and offspring …

In many species the mutation rate is higher in males than in females, a phenomenon denoted
as male mutation bias. This is often observed in animals where males produce many more …

Although bioinformatics is becoming increasingly central to research in the life sciences,
bioinformatics skills and knowledge are not well integrated into undergraduate biology …

Human papillomavirus subtype 16 (HPV16) is the primary cause of an increasing number of
head and neck squamous cell carcinomas (HNSCC), providing strong rationale for T-cell …

Background Elevated PD-L1 expression on tumor cells, a context associated with an adaptive
immune response, has been linked to the total burden of copy number variants (CNVs) in …

Y chromosomes have long been dismissed as “graveyards of genes,” but there is still much
to be learned from the genetic relics of genes that were once functional on the human Y. We …