One approach to quantifying the magnitude of confounding in observational studies is to
compare estimates with and without adjustment for a covariate, but this strategy is known to be …

The use of retrospective health care claims datasets is frequently criticized for the lack of
complete information on potential confounders. Utilizing patient’s health status–related …

Background Although more precise statistical language is sometimes used, for simplicity, in
this paper 1)“adjustment” refers to including a variable in a regression analysis unless …

Preeclampsia (PE) is a multisystem disorder with high maternal morbidity and mortality rates.
Currently, no practical therapeutic approach is available to prevent PE progression, except …

The accelerated failure time (AFT) model has been suggested as an alternative to the Cox
proportional hazards model. However, a parametric AFT model requires the specification of …

Background The Alzheimer's Disease Cooperative Study – Activities of Daily Living Scale
for use in Mild Cognitive Impairment (MCI), the ADCS-ADL-MCI, is an evaluation scale with …

The accelerated failure time model is an alternative to the Cox proportional hazards model
in survival analysis. However, conclusions regarding the associations of prognostic factors …

Background: Direct oral anticoagulants (DOACs) have widely replaced warfarin for stroke
prevention in nonvalvular atrial fibrillation. Our objective was to compare the safety and …

Inverse probability of treatment weighting (IPW) and targeted maximum likelihood estimation
(TMLE) are relatively new methods proposed for estimating marginal causal effects. TMLE …

Background: Targeted maximum likelihood estimation has been proposed for estimating
marginal causal effects, and is robust to misspecification of either the treatment or outcome …