A review of biosensor technologies for blood biomarkers toward monitoring cardiovascular diseases at the point-of-care
Cardiovascular diseases (CVDs) cause significant mortality globally. Notably, CVDs
disproportionately negatively impact underserved populations, such as those that are economically …
disproportionately negatively impact underserved populations, such as those that are economically …
Amphiphilic Particle-Stabilized Nanoliter Droplet Reactors with a Multimodal Portable Reader for Distributive Biomarker Quantification
Compartmentalization, leveraging microfluidics, enables highly sensitive assays, but the
requirement for significant infrastructure for their design, build, and operation limits access. …
requirement for significant infrastructure for their design, build, and operation limits access. …
Fabrication of 3D concentric amphiphilic microparticles to form uniform nanoliter reaction volumes for amplified affinity assays
Reactions performed in uniform microscale volumes have enabled numerous applications
in the analysis of rare entities (eg cells and molecules). Here, highly monodisperse aqueous …
in the analysis of rare entities (eg cells and molecules). Here, highly monodisperse aqueous …
Monodisperse drops templated by 3D-structured microparticles
The ability to create uniform subnanoliter compartments using microfluidic control has
enabled new approaches for analysis of single cells and molecules. However, specialized …
enabled new approaches for analysis of single cells and molecules. However, specialized …
[HTML][HTML] Computational cytometer based on magnetically modulated coherent imaging and deep learning
Detecting rare cells within blood has numerous applications in disease diagnostics. Existing
rare cell detection techniques are typically hindered by their high cost and low throughput. …
rare cell detection techniques are typically hindered by their high cost and low throughput. …
Engineering design of concentric amphiphilic microparticles for spontaneous formation of picoliter to nanoliter droplet volumes
G Destgeer, M Ouyang, D Di Carlo - Analytical Chemistry, 2021 - ACS Publications
Simple mixing of aqueous and oil solutions with amphiphilic particles leads to the spontaneous
formation of uniform reaction volumes (dropicles) that can enable numerous applications …
formation of uniform reaction volumes (dropicles) that can enable numerous applications …
Nanoplasmonic swarm biosensing using single nanoparticle colorimetry
M Ouyang, D Di Carlo - Biosensors and Bioelectronics, 2019 - Elsevier
We demonstrate a swarm biosensing platform that detects analyte based on the change in
plasmonic signal from thousands of single nanoparticles sensors, leading to increased …
plasmonic signal from thousands of single nanoparticles sensors, leading to increased …
An AC electrokinetics facilitated biosensor cassette for rapid pathogen identification
To develop a portable point-of-care system based on biosensors for common infectious
diseases such as urinary tract infection, the sensing process needs to be implemented within an …
diseases such as urinary tract infection, the sensing process needs to be implemented within an …
[HTML][HTML] Sensitizing drug-resistant cancer cells from blood using microfluidic electroporator
Direct assessment of patient samples holds unprecedented potential in the treatment of cancer.
Circulating tumor cells (CTCs) in liquid biopsies are a rapidly evolving source of primary …
Circulating tumor cells (CTCs) in liquid biopsies are a rapidly evolving source of primary …
[HTML][HTML] Microscale symmetrical electroporator array as a versatile molecular delivery system
Successful developments of new therapeutic strategies often rely on the ability to deliver
exogenous molecules into cytosol. We have developed a versatile on-chip vortex-assisted …
exogenous molecules into cytosol. We have developed a versatile on-chip vortex-assisted …