Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment
We present the results for CAPRI Round 46, the third joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of 20 targets including 14 homo‐oligomers …
prediction challenge. The Round comprised a total of 20 targets including 14 homo‐oligomers …
Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2
…, K Zohar, T Eliyahu, M Braitbard… - Proceedings of the …, 2021 - National Acad Sciences
Atomic structures of several proteins from the coronavirus family are still partial or unavailable.
A possible reason for this gap is the instability of these proteins outside of the cellular …
A possible reason for this gap is the instability of these proteins outside of the cellular …
[PDF][PDF] Structure of the human core centromeric nucleosome complex
…, T Van Eeuwen, M Slavin, M Braitbard… - Current Biology, 2019 - cell.com
Centromeric nucleosomes are at the interface of the chromosome and the kinetochore that
connects to spindle microtubules in mitosis. The core centromeric nucleosome complex (…
connects to spindle microtubules in mitosis. The core centromeric nucleosome complex (…
Integrative structure modeling: overview and assessment
M Braitbard, D Schneidman-Duhovny… - Annual review of …, 2019 - annualreviews.org
Integrative structure modeling computationally combines data from multiple sources of
information with the aim of obtaining structural insights that are not revealed by any single …
information with the aim of obtaining structural insights that are not revealed by any single …
[HTML][HTML] Cryo-EM structures of engineered active bc1-cbb3 type CIII2CIV super-complexes and electronic communication between the complexes
Respiratory electron transport complexes are organized as individual entities or combined
as large supercomplexes (SC). Gram-negative bacteria deploy a mitochondrial-like …
as large supercomplexes (SC). Gram-negative bacteria deploy a mitochondrial-like …
The Cdc48 N-terminal domain has a molecular switch that mediates the Npl4-Ufd1-Cdc48 complex formation
Cdc48 (VCP/p97) is a major AAA-ATPase involved in protein quality control, along with its
canonical cofactors Ufd1 and Npl4 (UN). Here, we present novel structural insights into the …
canonical cofactors Ufd1 and Npl4 (UN). Here, we present novel structural insights into the …
Dynamic Evolution of the Cthrc1 Genes, a Newly Defined Collagen-Like Family
…, TS Nir, M Bazarsky, M Braitbard… - Genome Biology and …, 2020 - academic.oup.com
Collagen triple helix repeat containing protein 1 (Cthrc1) is a secreted glycoprotein reported
to regulate collagen deposition and to be linked to the Transforming growth factor β/Bone …
to regulate collagen deposition and to be linked to the Transforming growth factor β/Bone …
Cryo-EM Structures of Respiratory bc1-cbb3 type CIII2CIV Supercomplex and Electronic Communication Between the Complexes
…, T VanEeuwen, Y Ozturk, HJ Kim, M Braitbard… - bioRxiv, 2020 - biorxiv.org
The respiratory electron transport complexes convey electrons from nutrients to oxygen and
generate a proton-motive force used for energy (ATP) production in cells. These enzymes …
generate a proton-motive force used for energy (ATP) production in cells. These enzymes …
The structural basis for the self-inhibition of DNA binding by apo-σ70
K Joron, J Zamel, S Dvir, N Kalisman, E Lerner - bioRxiv, 2022 - biorxiv.org
… Dina Schneidman and Merav Braitbard for providing PatchDock and assisting in the docking
procedures, (ii) Dr. Paul David Harris for consultation regarding mpH 2 MM analyses of …
procedures, (ii) Dr. Paul David Harris for consultation regarding mpH 2 MM analyses of …
[HTML][HTML] Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but
distinct cellular processes, endocytosis and autophagy, so its generation needs to be under …
distinct cellular processes, endocytosis and autophagy, so its generation needs to be under …