Lennox–Gastaut syndrome (LGS) is a severe epileptic and developmental encephalopathy
that is associated with a high rate of morbidity and mortality. It is characterized by multiple …

Objective To analyze the effectiveness and tolerability of perampanel across different
seizure types in routine clinical care of patients with idiopathic generalized epilepsy ( IGE ). …

Research in reversal learning has mainly focused on the functional role of dopamine and
striatal structures in driving behavior on the basis of classic reinforcement learning mechanisms…

Animal models of human anxiety often invoke a conflict between approach and avoidance [1,
2]. In these, a key behavioral assay comprises passive avoidance of potential threat and …

Normalization of brain images is a crucial step in MRI data analysis, especially when dealing
with abnormal brains. Although cost function masking (CFM) appears to successfully solve …

Recent accumulating evidence in animals and humans has shown that memory strengthening
occurs, at least partially, during sleep [1, 2] and relies on the covert reactivation of …

Importance Efficacy of cannabidiol has been demonstrated in seizures associated with
Lennox-Gastaut and Dravet syndromes but appears not yet to have been established in …

Background: Antibodies to glutamic acid decarboxylase (GAD ab) have been found in
patients with limbic encephalitis (LE) and chronic pharmacoresistant focal epilepsy (FE). The …

Integrating new information into existing schematic/semantic structures of knowledge is the
basis of learning in our everyday life as it enables structured representation of information …

Background Anti-NMDA receptor (NMDAR) encephalitis is associated with a post-acute stage
that is not well known. We aimed to describe the clinical features of this stage, similarities …