Do early-life viral infections cause asthma?
Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in
later childhood are well known. However, the question of whether such infections cause …
later childhood are well known. However, the question of whether such infections cause …
Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma
MMH Kusel, NH de Klerk, T Kebadze, V Vohma… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe lower respiratory infections (LRIs) and atopic sensitization have
been identified as independent risk factors for asthma. OBJECTIVE: The nature of potential …
been identified as independent risk factors for asthma. OBJECTIVE: The nature of potential …
[HTML][HTML] The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development
The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …
Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study
MMH Kusel, NH de Klerk, PG Holt… - The Pediatric …, 2006 - journals.lww.com
Objective: To investigate the role of all common respiratory viruses as upper and lower
respiratory tract pathogens in the first year of life. Study Design: This community-based birth …
respiratory tract pathogens in the first year of life. Study Design: This community-based birth …
Maternal serum vitamin D levels during pregnancy and offspring neurocognitive development
…, BJ Holt, M Serralha, PG Holt, MMH Kusel… - …, 2012 - publications.aap.org
OBJECTIVES: To determine the association between maternal serum 25(OH)-vitamin D
concentrations during a critical window of fetal neurodevelopment and behavioral, emotional, …
concentrations during a critical window of fetal neurodevelopment and behavioral, emotional, …
Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms
…, JE Tearne, PG Holt, PH Hart, MMH Kusel - Archives of women's …, 2014 - Springer
Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging
literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the …
literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the …
Maternal vitamin D status during pregnancy and bone mass in offspring at 20 years of age: a prospective cohort study
…, AJO Whitehouse, PH Hart, M Kusel… - Journal of Bone and …, 2014 - academic.oup.com
It is uncertain whether the vitamin D status of pregnant women influences bone mass of their
children. Cohort studies have yielded conflicting results; none have examined offspring at …
children. Cohort studies have yielded conflicting results; none have examined offspring at …
Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age
…, PH Hart, AJO Whitehouse, MM Kusel… - Annals of the …, 2014 - atsjournals.org
Rationale: Vitamin D deficiency is associated with chronic lung disease. We have previously
shown in an in vivo mouse model that maternal vitamin D deficiency is associated with …
shown in an in vivo mouse model that maternal vitamin D deficiency is associated with …
[PDF][PDF] Airway microbiota dynamics uncover a critical window for interplay of pathogenic bacteria and allergy in childhood respiratory disease
Repeated cycles of infection-associated lower airway inflammation drive the pathogenesis
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …
Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study
BACKGROUND: Atopy and asthma are commonly initiated during early life, and there is
increasing interest in the development of preventive treatments for at-risk children. However, …
increasing interest in the development of preventive treatments for at-risk children. However, …