In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects human cells by
binding its spike (S) glycoproteins to angiotensin-converting enzyme 2 (ACE2) receptors and …

KLF4 is an important regulator of cell-fate decision, including DNA damage response and
apoptosis. We identify a novel interplay between protein modifications in regulating KLF4 …

Microtubule (MT)–associated protein 7 (MAP7) is a required cofactor for kinesin-1–driven
transport of intracellular cargoes. Using cryo–electron microscopy and single–molecule …

Biomolecular conformational transitions are essential to biological functions. Most experimental
methods report on the long-lived functional states of biomolecules, but information about …

SARS-CoV-2 infection is initiated by binding of the receptor-binding domain (RBD) of its
spike glycoprotein to the peptidase domain (PD) of angiotensin-converting enzyme 2 (ACE2) …

Modeling protein flexibility constitutes a major challenge in accurate prediction of protein–ligand
and protein–protein interactions in docking simulations. The lack of a reliable method …

Background: Indirect evidences suggest that the I f blocker ivabradine may exert an
antiarrhythmic effect in ventricular myocardium in heart failure (HF) patients by inhibiting …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters human cells upon
binding of its spike (S) glycoproteins to ACE2 receptors. Several nanobodies neutralize SARS…

Introduction: Inappropriate use of oral anticoagulants (OACs) have not been well investigatedand,
however, may be frequent in real-world practice in patients with nonvalvular atrial …