Understanding neurite growth regulation remains a seminal problem in neurobiology.
During development and regeneration, neurite growth is modulated by neurotrophin-activated …

In this study, adhesions on individual filopodial shafts were shown to control veil (lamellar)
advance and to be modulated by guidance cues. Adhesions were detected in individual …

Injury to retinal ganglion cells (RGC), central nervous system neurons that relay visual
information to the brain, often leads to RGC axon degeneration and permanently lost visual …

Purpose We discuss recent advances in extracellular vesicle (EV) technology as biomarkers,
therapeutics, and drug delivery vehicles in the visual system with an emphasis on the retina…

Purpose.: Retinal ganglion cell (RGC) death and failed axonal regeneration after trauma or
disease, including glaucomatous and mitochondrial optic neuropathies, are linked …

Purpose.: Mammalian central nervous system neurons fail to regenerate after injury or disease,
in part due to a progressive loss in intrinsic axon growth ability after birth. Whether lost …

… Author links open overlay panel Wolfgang Pita-Thomas PhD a b , Michael B. Steketee PhD
a c , Stavros N. Moysidis MD a , Kinjal Thakor a , Blake Hampton BS a , Jeffrey L. Goldberg …

In peripheral nerve (PN) injuries requiring surgical repair, as in PN transection, cellular and
ECM remodeling at PN epineurial repair sites is hypothesized to reduce PN functional …

Injury to central nervous system (CNS) tissues in adult mammals often leads to neuronal loss,
scarring, and permanently lost neurologic functions, and this default healing response is …

Failed axon regeneration and retinal ganglion cell (RGC) death after trauma or disease,
including glaucomatous and mitochondrial optic neuropathies, are increasingly linked to …