[PDF][PDF] Genomic classification of cutaneous melanoma
…, E Curley, L Danilova, S D'Atri, T Davidsen, MA Davies… - Cell, 2015 - cell.com
We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
[HTML][HTML] A landscape of driver mutations in melanoma
…, M Noble, M Meyerson, JE Ladbury, MA Davies… - Cell, 2012 - cell.com
Despite recent insights into melanoma genetics, systematic surveys for driver mutations are
challenged by an abundance of passenger mutations caused by carcinogenic UV light …
challenged by an abundance of passenger mutations caused by carcinogenic UV light …
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
‘Reactive oxygen species’ (ROS) is a generic term that defines a wide variety of oxidant
molecules with vastly different properties and biological functions that range from signalling to …
molecules with vastly different properties and biological functions that range from signalling to …
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
…, MK Wong, SP Patel, SE Woodman, MA Davies… - Science, 2021 - science.org
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer,
but the effect of diet and supplements on this interaction is not well studied. We assessed …
but the effect of diet and supplements on this interaction is not well studied. We assessed …
Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.
MJ Davies, AC Thomas - British heart journal, 1985 - ncbi.nlm.nih.gov
The clinical management of acute myocardial infarc-tion and crescendo angina as well as
the prevention of sudden ischaemic death require accurate knowledge of the underlying …
the prevention of sudden ischaemic death require accurate knowledge of the underlying …
A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates.
1. A new method has been developed for measuring the total antioxidant capacity of body
fluids and drug solutions, based on the absorbance of the ABTS.+ radical cation. 2. An …
fluids and drug solutions, based on the absorbance of the ABTS.+ radical cation. 2. An …
B cells and tertiary lymphoid structures promote immunotherapy response
Abstract Treatment with immune checkpoint blockade (ICB) has revolutionized cancer therapy.
Until now, predictive biomarkers 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 – 10 and strategies to augment …
Until now, predictive biomarkers 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 – 10 and strategies to augment …
Biochemistry and pathology of radical-mediated protein oxidation
… formation may be of limited importance compared with Michael addition reactions [73,74].
In … by Michael addition of 4-HNE [75]. With dialdehydes, Schiffbase formation and Michael …
In … by Michael addition of 4-HNE [75]. With dialdehydes, Schiffbase formation and Michael …
Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death
MJ Davies, A Thomas - New England Journal of Medicine, 1984 - Mass Medical Soc
The nature of the pathologic lesion in sudden cardiac ischemic death is in dispute. Among
100 subjects who died of ischemic heart disease in less than six hours, coronary thrombi were …
100 subjects who died of ischemic heart disease in less than six hours, coronary thrombi were …
[HTML][HTML] Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led researchers …
disease are emerging throughout biological sciences. This development has led researchers …