Developmental traumatology: The psychobiological development of maltreated children and its implications for research, treatment, and policy

MD De Bellis - Development and psychopathology, 2001 - cambridge.org
In this review, a developmental traumatology model of child maltreatment and the risk for the
intergenerational cycle of abuse and neglect using a mental health or posttraumatic stress …

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing …

…, TD Geracioti Jr, MD DeBellis… - Proceedings of the …, 2000 - National Acad Sciences
Both stress-system activation and melancholic depression are characterized by fear,
constricted affect, stereotyped thinking, and similar changes in autonomic and neuroendocrine …

Neurodevelopmental biology associated with childhood sexual abuse

MD De Bellis, EG Spratt, SR Hooper - Journal of child sexual abuse, 2011 - Taylor & Francis
Child maltreatment appears to be the single most preventable cause of mental illness and
behavioral dysfunction in the United States. Few published studies examine the …

Development of the corpus callosum in childhood, adolescence and early adulthood

MS Keshavan, VA Diwadkar, M DeBellis, E Dick… - Life sciences, 2002 - Elsevier
The corpus callosum (CC) is the major commissure connecting the cerebral hemispheres
and there is evidence of its continuing development into young adulthood [Ann. Neurol. 34 (…

Developmental traumatology part II: brain development

MD De Bellis, MS Keshavan, DB Clark, BJ Casey… - Biological …, 1999 - Elsevier
Background: Previous investigations suggest that maltreated children with a diagnosis of
posttraumatic stress disorder (PTSD) evidence alterations of biological stress systems. …

Treating traumatized children: Clinical implications of the psychobiology of posttraumatic stress disorder

JA Cohen, JM Perel, MD DeBellis… - … Violence, & Abuse, 2002 - journals.sagepub.com
There is growing evidence that child maltreatment and posttraumatic stress disorder result in
numerous neurobiological alterations in children and adolescents, including abnormalities …

Developmental traumatology part I: Biological stress systems

MD De Bellis, AS Baum, B Birmaher, MS Keshavan… - Biological …, 1999 - Elsevier
Background: This investigation examined the relationship between trauma, psychiatric
symptoms and urinary free cortisol (UFC) and catecholamine (epinephrine [EPI], norepinephrine […

The biological effects of childhood trauma

MD De Bellis, A Zisk - Child and Adolescent Psychiatric …, 2014 - childpsych.theclinics.com
Trauma in childhood has serious consequences for its victims and for society. For the
purposes of this critical review, childhood trauma is defined according to the

Sex differences in brain maturation during childhood and adolescence

MD De Bellis, MS Keshavan, SR Beers, J Hall… - Cerebral …, 2001 - academic.oup.com
Brain development during childhood and adolescence is characterized by both progressive
myelination and regressive pruning processes. However, sex differences in brain maturation …

Brain structures in pediatric maltreatment-related posttraumatic stress disorder: a sociodemographically matched study

MD De Bellis, MS Keshavan, H Shifflett, S Iyengar… - Biological …, 2002 - Elsevier
BACKGROUND: Previous investigations suggest that maltreated children evidence alterations
of chemical mediators of stress and adverse brain development. Previous anatomical …