Simulation comprises an indispensable set of technological tools and methods for the
successful implementation of digital manufacturing, since it allows for the experimentation and …

Background After neoadjuvant chemoradiotherapy for oesophageal cancer, roughly half of
the patients with squamous cell carcinoma and a quarter of those with adenocarcinoma have …

Background Neoadjuvant chemoradiotherapy (nCRT) plus surgery is a standard treatment
for locally advanced oesophageal cancer. With this treatment, 29% of patients have a …

Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a congenital visceral
myopathy characterized by severe dilation of the urinary bladder and defective intestinal …

Manufacturers and service providers are called to design, plan and operate globalized
manufacturing networks, addressing to challenges such as ever-decreasing lifecycles and …

Metastases expressing tumor-specific receptors can be targeted and treated by binding of
radiolabeled peptides (peptide receptor radionuclide therapy or PRRT). For example, patients …

Objective International guidelines recommend endoscopic surveillance of premalignant
gastric lesions. However, the diagnostic yield and preventive effect require further study. We …

The transition from local economies to the global competitive landscape and the current
fluctuating customer demands drives a never-ending transformation of manufacturing systems. …

GW572016 is a dual EGFR-ErbB2 inhibitor that has promise as an anticancer agent. Two
phase I studies were conducted to determine the safety, tolerability and pharmacokinetics of …

The 2009 eruption of Redoubt Volcano, Alaska was particularly well monitored for volcanic
gas emissions. We report 35 airborne measurements of CO 2 , SO 2 , and H 2 S emission …