Background Many college students register each semester for courses, leading to productive
careers and fulfilled lives. During this time, the students have to manage many stressors …

The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic
architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of …

Obesity and hypertension, which often coexist, are major risk factors for heart failure and are
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …

Known for its clear presentation style, single-author voice, and focus on content most relevant
to clinical and pre-clinical students, Guyton and Hall Textbook of Medical Physiology, 14th …

Background We determined if the sodium glucose co‐transporter 2 inhibitor empagliflozin
attenuates pressure overload‐induced heart failure in non‐diabetic mellitus mice by direct …

Excess weight gain, especially when associated with increased visceral adiposity, is a
major cause of hypertension, accounting for 65% to 75% of the risk for human primary (essential) …

The angiotensin converting enzyme (ACE) 2 is a cell surface protein used for entry into type
II pneumocytes and other tissues by severe acute respiratory syndrome coronavirus 2 …

Obesity is a major risk factor for essential hypertension, diabetes, and other comorbid conditions
that contribute to development of chronic kidney disease. Obesity raises blood pressure …

Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide
deaths, respectively, due largely to broad increased risk for disease and injury 1 , 2 , 3 – …

Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …