User profiles for Michael Freissmuth

Michael Freissmuth

Medical University of Vienna
Verified email at meduniwien.ac.at
Cited by 18928

Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk

…, G Alk, R Roka, K Glaser, M Freissmuth - Annals of …, 2002 - journals.lww.com
Objective To evaluate the effect of recurrent nerve dissection on the incidence of recurrent
laryngeal nerve injury (RLNI) and to analyze the performance of individual surgeons. …

The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and d-amphetamine

T Steinkellner, M Freissmuth, HH Sitte, T Montgomery - 2011 - degruyter.com
Amphetamine (‘Speed’), methamphetamine (‘Ice’) and its congener 3,4-methylenedioxymethamphetamine
(MDMA; ‘Ecstasy’) are illicit drugs abused worldwide for their euphoric and …

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

…, PE Dawson, DJ Craik, M Freissmuth… - Proceedings of the …, 2013 - National Acad Sciences
Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide
bonds that confer them with exceptional stability. They were originally discovered in …

[PDF][PDF] A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

…, C Bock, L Kenner, G Hoefler, M Freissmuth… - Cancer cell, 2013 - cell.com
In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels
in lymphoid malignancies. In a model for p185 BCR-ABL+ B-acute lymphoid leukemia, we …

[HTML][HTML] Amphetamines, new psychoactive drugs and the monoamine transporter cycle

HH Sitte, M Freissmuth - Trends in pharmacological sciences, 2015 - cell.com
In monoaminergic neurons, the vesicular transporters and the plasma membrane transporters
operate in a relay. Amphetamine and its congeners target this relay to elicit their actions: …

The reverse operation of Na+/Cl‐coupled neurotransmitter transporters – why amphetamines take two to tango

HH Sitte, M Freissmuth - Journal of neurochemistry, 2010 - Wiley Online Library
Sodium‐chloride coupled neurotransmitter transporters achieve reuptake of their physiological
substrate by exploiting the pre‐existing sodium‐gradient across the cellular membrane. …

Reverse intrinsic activity of antagonists on G protein-coupled receptors

W Schütz, M Freissmuth - Trends in pharmacological sciences, 1992 - cell.com
… In this Principles article, Wolfgang Schiitz and Michael Freissmuth show how considerable
evidence has now been accumulated for G proteincoupled receptors that antagonists not only …

Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury

M Hermann, C Hellebart, M Freissmuth - Annals of surgery, 2004 - journals.lww.com
Objective: We evaluated the ability of neuromonitoring to predict postoperative outcome in
patients undergoing thyroid surgery for different indications. Summary Background Data: …

G proteins control diverse pathways of transmembrane signaling1

M Freissmuth, PJ Casey, AG Gilman - The FASEB journal, 1989 - Wiley Online Library
Hormones, neurotransmitters, and autacoids interact with specific receptors and thereby
trigger a series of molecular events that ultimately produce their biological effects. These …

Adenosine receptors: G protein-mediated signalling and the role of accessory proteins

M Klinger, M Freissmuth, C Nanoff - Cellular signalling, 2002 - Elsevier
Ever since the discovery of the effects of adenosine in the circulation, adenosine receptors
continue to represent a promising drug target. Firstly, this is due to the fact that the receptors …