Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic
cardiovascular complications up to 1 year after infection. Although the systemic inflammatory …

Long noncoding RNAs (lncRNAs) have emerged as critical regulators of gene expression,
yet their contribution to immune regulation in humans remains poorly understood. Here, we …

Angiopoietin-like protein 3 (ANGPTL3) is a hepatically secreted protein and therapeutic
target for reducing plasma triglyceride-rich lipoproteins and low-density lipoprotein (LDL) …

Atherosclerosis is fueled by a failure to resolve lipid-driven inflammation within the
vasculature that drives plaque formation. Therapeutic approaches to reverse atherosclerotic …

Targeted RNA sequencing (RNA-seq) aims to focus coverage on areas of interest that are
inadequately sampled in standard RNA-seq experiments. Here we present multiplexed primer …

We generate high-precision measurements of the in vivo rates of both chemical steps of pre-mRNA
splicing across the genome-wide complement of substrates in yeast by coupling …

The study of pre-mRNA splicing has been greatly aided by the advent of RNA sequencing (RNA-seq),
which enables the genome-wide detection of discrete splice isoforms. …

Background Previously, we had developed and manufactured an oligonucleotide fluorescence
in situ hybridization (OligoFISH) probe panel based on the most clinically sensitive …

Targeted RNA-sequencing aims to focus coverage on areas of interest that are inadequately
sampled in standard RNA-sequencing experiments. Here we present a novel approach for …

The Czech Republic has a long history of product excellence recognizable in such diverse
areas as beer, weapons and shoe manufacture. Moreover, many of the ideas regarded as …