5-Fluorouracil (5FU) and oxaliplatin are standard therapy for metastatic colorectal cancer (CRC),
but the development of chemoresistance is inevitable. Because cancer stem cells (CSC…

Purpose: Epithelial-to-mesenchymal transition (EMT) is a process whereby cells acquire
molecular alterations that facilitate cell motility and invasion. In preliminary studies, we …

Hypoxia stimulates a number of pathways critical to cancer cell survival, including the activation
of vascular endothelial growth factor (VEGF) transcription. In normal fibroblasts, hypoxia-…

Endoglin (CD105) is an accessory protein of the transforming growth factor-β receptor system
expressed on vascular endothelial cells. Mutation of the endoglin gene is associated with …

Composed of up to 1,000 phospho-anhydride bond-linked phosphate monomers, inorganic
polyphosphate (polyP) is one of the most ancient, conserved, and enigmatic molecules in …

Our laboratory has shown that vascular endothelial growth factor receptor-1 (VEGFR-1)
expression on human pancreatic cancer cell lines mediates cell migration and invasion. …

Hypochlorous acid (HOCl), the active ingredient of household bleach, is the most common
disinfectant in medical, industrial, and domestic use and plays an important role in microbial …

A total of 502 Listeria monocytogenes isolates from food and 492 from humans were subtyped
by EcoRI ribotyping and PCR-restriction fragment length polymorphism analysis of the …

BACKGROUND Vascular endothelial growth factor receptor‐1 (VEGFR‐1) is one of three
receptor tyrosine kinases for VEGF, a key regulator of angiogenesis in cancer. Although …

Listeria monocytogenes is a gram-positive bacterium with a Jekyll and Hyde personality (108):
it is well adapted as a saprophyte for peaceful survival in soil and decaying vegetation (Dr…