User profiles for Michael J. Rust
Michael J RustAssociate Professor of Molecular Genetics and Cell Biology and of Physics, University of … Verified email at uchicago.edu Cited by 16217 |
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
We have developed a high-resolution fluorescence microscopy method based on high-accuracy
localization of photoswitchable fluorophores. In each imaging cycle, only a fraction of …
localization of photoswitchable fluorophores. In each imaging cycle, only a fraction of …
Visualizing infection of individual influenza viruses
M Lakadamyali, MJ Rust… - Proceedings of the …, 2003 - National Acad Sciences
Influenza is a paradigm for understanding viral infections. As an opportunistic pathogen
exploiting the cellular endocytic machinery for infection, influenza is also a valuable model …
exploiting the cellular endocytic machinery for infection, influenza is also a valuable model …
[HTML][HTML] Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes
Cells rely on the correct sorting of endocytic ligands and receptors for proper function. Early
endosomes have been considered as the initial sorting station where cargos for degradation …
endosomes have been considered as the initial sorting station where cargos for degradation …
[HTML][HTML] Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells
HM Van Der Schaar, MJ Rust, C Chen… - PLoS …, 2008 - journals.plos.org
Dengue virus (DENV) is an enveloped RNA virus that causes the most common arthropod-borne
infection worldwide. The mechanism by which DENV infects the host cell remains …
infection worldwide. The mechanism by which DENV infects the host cell remains …
Assembly of endocytic machinery around individual influenza viruses during viral entry
Most viruses enter cells via receptor-mediated endocytosis. However, the entry mechanisms
used by many of them remain unclear. Also largely unknown is the way in which viruses are …
used by many of them remain unclear. Also largely unknown is the way in which viruses are …
Ordered phosphorylation governs oscillation of a three-protein circadian clock
The simple circadian oscillator found in cyanobacteria can be reconstituted in vitro using
three proteins—KaiA, KaiB, and KaiC. The total phosphorylation level of KaiC oscillates with a …
three proteins—KaiA, KaiB, and KaiC. The total phosphorylation level of KaiC oscillates with a …
[HTML][HTML] Endocytosis of influenza viruses
Receptor-mediated endocytosis is known to play an important role in the entry of many
viruses into host cells. However, the exact internalization mechanism has, until recently, …
viruses into host cells. However, the exact internalization mechanism has, until recently, …
[HTML][HTML] Imaging poliovirus entry in live cells
Viruses initiate infection by transferring their genetic material across a cellular membrane
and into the appropriate compartment of the cell. The mechanisms by which animal viruses, …
and into the appropriate compartment of the cell. The mechanisms by which animal viruses, …
Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking
HM van der Schaar, MJ Rust, BL Waarts… - Journal of …, 2007 - Am Soc Microbiol
In this study, we investigated the cell entry characteristics of dengue virus (DENV) type 2 strain
S1 on mosquito, BHK-15, and BS-C-1 cells. The concentration of virus particles measured …
S1 on mosquito, BHK-15, and BS-C-1 cells. The concentration of virus particles measured …
Functionalized nano interdigitated electrodes arrays on polymer with integrated microfluidics for direct bio-affinity sensing using impedimetric measurement
This paper presents a fully integrated nano interdigitated electrodes array (nIDA) and
microfluidic system on polymer substrate. It can be used as a miniaturized, sensitive, and easy-to-…
microfluidic system on polymer substrate. It can be used as a miniaturized, sensitive, and easy-to-…