Importance Novel sensitive methods for detection and monitoring of residual disease can
improve postoperative risk stratification with implications for patient selection for adjuvant …

PURPOSE Novel sensitive methods for early detection of relapse and for monitoring therapeutic
efficacy may have a huge impact on risk stratification, treatment, and ultimately outcome …

Purpose: We investigated whether detection of ctDNA after resection of colorectal cancer
identifies the patients with the highest risk of relapse and, furthermore, whether longitudinal …

Overtreatment with cisplatin-based chemotherapy is a major issue in the management of
muscle-invasive bladder cancer (MIBC), and currently none of the reported biomarkers for …

Calcium ions (Ca 2+ ) have an important role as secondary messengers in numerous signal
transduction processes 1 , 2 , 3 , 4 , and cells invest much energy in controlling and …

Of the patients undergoing radical cystectomy, 20–80% experience relapse. Minimally
invasive methods for early detection of metastatic relapse after cystectomy and for monitoring …

This paper reports on a simulation-based study that investigated the demand response potential
of a model predictive controller (MPC) for space heating defined to minimize a weighted …

Background The physical demands and high rates of musculoskeletal injury among practicing
orthopaedic surgeons have been previously recognized in the literature. However, there …

Previous studies have identified significant demand response (DR) potentials in using economic
model predictive control (E-MPC) of space heating to exploit the inherent thermal mass …

In ultra-low temperature district heating the supply temperature is less than required to heat
the domestic hot water and a heat pump is therefore often proposed to raise the temperature. …