User profiles for Michael L. Nicholson

Prof. ML Nicholson

Verified email at cam.ac.uk
Cited by 16316

[HTML][HTML] Rapamycin in transplantation: a review of the evidence

RN Saunders, MS Metcalfe, ML Nicholson - Kidney international, 2001 - Elsevier
… Serum Chol and TGs were elevated (Chol 5.8 mmol/L, TGs 4.6 mmol/L), but only one patient
required treatment in an initial pilot study 64 . Hyperlipidemia appears less marked than …

[HTML][HTML] Normothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial

…, GC Oniscu, BL Phillips, L Bates, ML Nicholson - Nature medicine, 2023 - nature.com
Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still severely
limited by a lack of suitable organ donors. Kidneys from donation after circulatory death (…

Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates

…, CM Philpott, MT Chorbadjian, ML Nicholson… - …, 2003 - journals.lww.com
Background. Clinical trials in renal transplantation must use surrogate markers of long-term
graft survival if conclusions are to be drawn at acceptable speed and cost. Morphologic …

[HTML][HTML] A prospective randomized trial of three different sizes of core-cutting needle for renal transplant biopsy

ML Nicholson, TJ Wheatley, TM Doughman, SA White… - Kidney international, 2000 - Elsevier
… All biopsies were performed for cases of acute allograft dysfunction (creatinine rise of ≥30
μmol/L) or to monitor the response to antirejection treatment. The post-transplant drug …

First in man renal transplantation after ex vivo normothermic perfusion

SA Hosgood, ML Nicholson - Transplantation, 2011 - journals.lww.com
Background. Normothermic perfusion is an alternative but little studied method of organ
preservation. Herein, we report the first case of ex vivo normothermic renal transplant perfusion …

Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms

AD Barlow, ML Nicholson, TP Herbert - Diabetes, 2013 - Am Diabetes Assoc
Rapamycin is used frequently in both transplantation and oncology. Although historically
thought to have little diabetogenic effect, there is growing evidence of β-cell toxicity. This …

[HTML][HTML] A comparison of the results of renal transplantation from non–heart-beating, conventional cadaveric, and living donors

ML Nicholson, MS Metcalfe, SA White, JR Waller… - Kidney international, 2000 - Elsevier
… The mean (SD) serum creatinine at 12 months was 179 (73) μmol/L in NHBD kidneys
compared with 152 (57) μmol/L for HBD kidneys and 138 (44) μmol/L for LD kidneys. The actuarial …

A study of the position of the mandibular foramen in the adult human mandible

ML Nicholson - The anatomical record, 1985 - Wiley Online Library
Eighty dry, adult human mandibles of East Indian ethnic origin and bilateral eruption of third
molar teeth were examined to measure the location of the mandibular foramen. The position …

[HTML][HTML] Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal …

…, C Wilson, C Callaghan, D Collett, ML Nicholson - BMJ open, 2017 - bmjopen.bmj.com
Introduction Ex vivo normothermic perfusion (EVNP) is a novel technique that reconditions
the kidney and restores renal function prior to transplantation. Phase I data from a series of …

Normothermic machine perfusion of the kidney: better conditioning and repair?

…, E van Heurn, ML Nicholson - Transplant …, 2015 - Wiley Online Library
Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival. …