User profiles for Michael Letko
 | Michael LetkoWashington State University Verified email at wsu.edu Cited by 5648 |
[HTML][HTML] Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
Over the past 20 years, several coronaviruses have crossed the species barrier into humans,
causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV was first …
causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV was first …
[HTML][HTML] Why is there low morbidity and mortality of COVID-19 in Africa?
Three months since the detection of the first COVID-19 case in Africa, almost all countries of
the continent continued to report lower morbidity and mortality than the global trend, …
the continent continued to report lower morbidity and mortality than the global trend, …
[HTML][HTML] Functional assessment of cell entry and receptor usage for lineage B β-coronaviruses, including 2019-nCoV
Over the past 20 years, several coronaviruses have crossed the species barrier into humans,
causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV was first …
causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV was first …
[HTML][HTML] An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines
Spillover of sarbecoviruses from animals to humans has resulted in outbreaks of severe acute
respiratory syndrome SARS-CoVs and the ongoing COVID-19 pandemic. Efforts to identify …
respiratory syndrome SARS-CoVs and the ongoing COVID-19 pandemic. Efforts to identify …
[HTML][HTML] Bat-borne virus diversity, spillover and emergence
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah …
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah …
Origin of the HIV-1 group O epidemic in western lowland gorillas
…, M Gray, A Cournil, M Ooms, M Letko… - Proceedings of the …, 2015 - National Acad Sciences
HIV-1, the cause of AIDS, is composed of four phylogenetic lineages, groups M, N, O, and P,
each of which resulted from an independent cross-species transmission event of simian …
each of which resulted from an independent cross-species transmission event of simian …
Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection
K Rosenke, K Meade-White, M Letko… - Emerging microbes & …, 2020 - Taylor & Francis
Following emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …
[HTML][HTML] Adaptive evolution of MERS-CoV to species variation in DPP4
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) likely originated in bats and
passed to humans through dromedary camels; however, the genetic mechanisms underlying …
passed to humans through dromedary camels; however, the genetic mechanisms underlying …
[PDF][PDF] HIV-1 Vif adaptation to human APOBEC3H haplotypes
M Ooms, B Brayton, M Letko, SM Maio, CD Pilcher… - Cell host & …, 2013 - cell.com
Several human APOBEC3 deaminases can inhibit HIV-1 replication in vitro. HIV-1 Vif
counteracts this restriction by targeting APOBEC3 for proteasomal degradation. Human …
counteracts this restriction by targeting APOBEC3 for proteasomal degradation. Human …
[HTML][HTML] Anti-spike antibodies and neutralising antibody activity in people living with HIV vaccinated with COVID-19 mRNA-1273 vaccine: a prospective single-centre …
Background Vaccines against COVID-19 are a powerful tool to control the current SARS-CoV-2
pandemic. A thorough description of their immunogenicity among people living with HIV (…
pandemic. A thorough description of their immunogenicity among people living with HIV (…