User profiles for Michael Newnham

Michael Newnham

Associate Professor, University of Birmingham
Verified email at bham.ac.uk
Cited by 1475

COVID-19, immunothrombosis and venous thromboembolism: biological mechanisms

J Loo, DA Spittle, M Newnham - Thorax, 2021 - thorax.bmj.com
Thrombotic events that frequently occur in COVID-19 are predominantly venous thromboemboli
(VTE) and are associated with increasing disease severity and worse clinical outcomes. …

[HTML][HTML] Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

…, S Moledina, D Montani, M Newnham… - Nature …, 2018 - nature.com
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …

[HTML][HTML] Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

…, D Montani, SD Nathan, M Newnham… - The lancet respiratory …, 2019 - thelancet.com
Background Rare genetic variants cause pulmonary arterial hypertension, but the contribution
of common genetic variation to disease risk and natural history is poorly characterised. …

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

…, S Moledina, D Montani, M Newnham… - Circulation, 2017 - Am Heart Assoc
Background: Pulmonary arterial hypertension (PAH) is a rare disease with an emerging
genetic basis. Heterozygous mutations in the gene encoding the bone morphogenetic protein …

A multicenter study of anticoagulation in operable chronic thromboembolic pulmonary hypertension

K Bunclark, M Newnham, YD Chiu… - … of Thrombosis and …, 2020 - Wiley Online Library
Background Chronic thromboembolic pulmonary hypertension (CTEPH) is an uncommon
complication of acute pulmonary emboli necessitating lifelong anticoagulation. Despite this, …

[HTML][HTML] The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

M Newnham, K South, M Bleda… - European …, 2019 - Eur Respiratory Soc
Chronic thromboembolic pulmonary hypertension (CTEPH) is an important consequence of
pulmonary embolism that is associated with abnormalities in haemostasis. We investigated …

CAMPHOR score: patient-reported outcomes are improved by pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

M Newnham, K Bunclark, N Abraham… - European …, 2020 - Eur Respiratory Soc
Background Pulmonary endarterectomy (PEA) is the recommended treatment for eligible
patients with chronic thromboembolic pulmonary hypertension (CTEPH). The Cambridge …

Cardiovascular disease in chronic obstructive pulmonary disease: a narrative review

…, AS Mohammed, AM Turner, M Newnham - Thorax, 2022 - thorax.bmj.com
Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of
cardiovascular disease (CVD) and concomitant disease leads to reduced quality of life, increased …

Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis

…, JM Martin, S Moledina, M Newnham… - European …, 2019 - Eur Respiratory Soc
While traffic and air pollution exposure is associated with increased mortality in numerous
diseases, its association with disease severity and outcomes in pulmonary arterial …

A comparison of the enactment and consequences of emotional labor between frontline hotel workers in two contrasting societal cultures

MP Newnham - Journal of Human Resources in Hospitality & …, 2017 - Taylor & Francis
Emotional labor is compared between hotel workers in the Philippines and Australia based
on idiocentrism and allocentrism dimensions. Employees were surveyed using the …