Nanopore technologies are being developed for fast and direct sequencing of single DNA
molecules through detection of ionic current modulations as DNA passes through a pore's …

Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA
sequencing technology. The simplest form of nanopore DNA sequencing utilizes the hypothesis …

The cell walls of mycobacteria form an exceptional permeability barrier, and they are
essential for virulence. They contain extractable lipids and long-chain mycolic acids that are …

Mycobacteria have low-permeability outer membranes that render them resistant to most
antibiotics. Hydrophilic nutrients can enter by way of transmembrane-channel proteins called …

Nanopores hold great promise as single-molecule analytical devices and biophysical model
systems because the ionic current blockades they produce contain information about the …

Copper (Cu) is essential for many biological processes, but is toxic when present in excessive
amounts. In this study, we provide evidence that Cu plays a crucial role in controlling …

Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial pathogen. …

The cell wall is a major virulence factor of Mycobacterium tuberculosis and contributes to its
intrinsic drug resistance. Recently, cryo-electron microscopy showed that mycobacterial cell …

Mycobacteria protect themselves with an outer lipid bilayer, which is the thickest biological
membrane hitherto known and has an exceptionally low permeability rendering mycobacteria …

Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host
immune system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules, …