Competency‐based applications have gained a foothold in HR practice worldwide; however,
changes in the business environment and the structure of work itself are challenging the …

As a Mendelian neurodegenerative disorder, the genetic risk of Huntington's disease (HD)
is conferred entirely by an HTT CAG repeat expansion whose length is the primary …

Pancreatic ductal adenocarcinoma (PDAC) is a highly devastating disease with poor prognosis
and rising incidence. Late detection and a particularly aggressive biology are the major …

Variable, glutamine-encoding, CAA interruptions indicate that a property of the uninterrupted
HTT CAG repeat sequence, distinct from the length of huntingtin's polyglutamine segment, …

OBJECTIVE: Glucosamine (GLN) and chondroitin sulfate (CS) are widely used to alleviate
symptoms of osteoarthritis (OA). However, the mechanism(s) of action of these nutraceuticals …

Decreased bone mass, osteoporosis, and increased fracture rates are common skeletal
complications in patients with insulin-dependent diabetes mellitus (IDDM; type I diabetes). IDDM …

Background The majority of Huntington's disease (HD) mutation carriers experience some
psychopathology during their lifetime, varying from irritability to psychosis, but prevalences of …

Background Huntington's disease is caused by a CAG repeat expansion in the huntingtin
gene, HTT. Age at onset has been used as a quantitative phenotype in genetic analysis …

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by
a CAG repeat expansion in the HTT gene. HD usually manifests in adult life, causing motor …

There is considerable evidence that Gilles de la Tourette syndrome (TS) is due to frontal–striatal
dysfunction. Here we determine whether adaptive cortical changes occur that might …