Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission
Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing
between countries, and existing programmes focus on screening symptomatic rather than …
between countries, and existing programmes focus on screening symptomatic rather than …
The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of …
…, AJ Carmichael, K Mynard, X Jin, MP Weekes… - Journal of …, 1996 - Am Soc Microbiol
Cytotoxic T lymphocytes (CTL) appear to play an important role in the control of human
cytomegalovirus (HCMV) in the normal virus carrier: previous studies have identified peripheral …
cytomegalovirus (HCMV) in the normal virus carrier: previous studies have identified peripheral …
[PDF][PDF] Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
…, JED Thaventhiran, EJM Toonen, MP Weekes… - Immunity, 2021 - cell.com
The kinetics of the immune changes in COVID-19 across severity groups have not been
rigorously assessed. Using immunophenotyping, RNA sequencing, and serum cytokine analysis…
rigorously assessed. Using immunophenotyping, RNA sequencing, and serum cytokine analysis…
[HTML][HTML] Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study
…, T Feltwell, S Forrest, S Sridhar, MP Weekes… - The Lancet infectious …, 2020 - thelancet.com
Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
[HTML][HTML] Quantitative temporal viromics: an approach to investigate host-pathogen interaction
A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host interaction…
the course of a productive infection could provide dynamic insights into virus-host interaction…
Quantitation and prognostic value of breast cancer angiogenesis: comparison of microvessel density, Chalkley count, and computer image analysis
In some studies of breast cancer, quantitation of immunohistochemically highlighted
microvessel ‘hot spots’ has been shown to be a powerful prognostic tool. However, the antibody …
microvessel ‘hot spots’ has been shown to be a powerful prognostic tool. However, the antibody …
NOTCH1 mediates a switch between two distinct secretomes during senescence
Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse
secretome, which provides complex functionality for senescent cells within the tissue …
secretome, which provides complex functionality for senescent cells within the tissue …
Covid-19: should the public wear face masks?
B Javid, MP Weekes, NJ Matheson - Bmj, 2020 - bmj.com
When covid-19 became a global health emergency, there was a visible contrast between the
responses of citizens in east Asia and the rest of the world. In east Asia, wearing of masks …
responses of citizens in east Asia and the rest of the world. In east Asia, wearing of masks …
The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone …
MP Weekes, MR Wills, KIM Mynard… - Journal of …, 1999 - Am Soc Microbiol
Human cytomegalovirus (HCMV)-specific CD8 + cytotoxic T lymphocytes (CTL) appear to
play an important role in the control of virus replication and in protection against HCMV-related …
play an important role in the control of virus replication and in protection against HCMV-related …
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
Plasmodium vivax shows a strict host tropism for reticulocytes. We identified transferrin
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …