Obtaining an accurate measure of how recombination rates vary across the genome has
implications for understanding the molecular basis of recombination, its evolutionary …

The bacterial phage shock protein (Psp) response functions to help cells manage the impacts
of agents impairing cell membrane function. The system has relevance to biotechnology …

Developing mechanistic models has become an integral aspect of systems biology, as has
the need to differentiate between alternative models. Parameterizing mathematical models …

Approximate Bayesian computation (ABC) methods can be used to evaluate posterior
distributions without having to calculate likelihoods. In this paper, we discuss and apply an ABC …

Candida species are the most common cause of opportunistic fungal infection worldwide.
Here we report the genome sequences of six Candida species and compare these and related …

After the completion of the human and other genome projects it emerged that the number of
genes in organisms as diverse as fruit flies, nematodes, and humans does not reflect our …

The ability to summarize observations using explanatory and predictive theories is the
greatest strength of modern science. A theoretical framework is perceived as particularly …

Most studies of networks have only looked at small subsets of the true network. Here, we
discuss the sampling properties of a network's degree distribution under the most parsimonious …

Kuru is an acquired prion disease largely restricted to the Fore linguistic group of the Papua
New Guinea Highlands, which was transmitted during endocannibalistic feasts. …

While single-cell gene expression experiments present new challenges for data processing,
the cell-to-cell variability observed also reveals statistical relationships that can be used by …