Peptide cleanup is essential for the removal of contaminating substances that may be
introduced during sample preparation steps in bottom-up proteomic workflows. Recent studies …

Pseudomonas aeruginosa causes life‐threatening infections in compromised and cystic
fibrosis patients. Pathogenesis stems from a number of virulence factors, including four type III …

Targeting mRNAs via seed region pairing is the canonical mechanism by which microRNAs
(miRNAs) regulate cellular functions and disease processes. Emerging evidence suggests …

Simple Summary There is an unmet medical need for new and potent pharmacological
inhibitor drugs for the protein Stat5 that would be orally bioavailable for treatment of several …

Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in
many patients because of profound endocrine and neurologic dysfunction. To date, no clear …

… Michael Pereckas … Michael Pereckas - Department of Chemistry and School of
Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53706, and The Protein …

The O‐GlcNAc post‐translational modification is reversibly added onto intracellular proteins.
It is a unique glucose rheostat for cell signaling relying on the availability of UDP‐GlcNAc, …

Lyme arthritis (LA), caused by Borrelia burgdorferi (Bb), is often accompanied by autoimmune
T and B cell responses, but the mechanisms of infection-induced autoimmunity are unclear…

Targeting mRNA via seed region pairing is the canonical mechanism by which microRNAs (miRNAs)
regulate cellular functions and disease processes. Emerging evidence suggests …

Background: Lyme arthritis (LA) is caused by infection with the Lyme disease spirochete
Borrelia burgdorferi (Bb) and in humans is often accompanied by autoimmune T and B cell …