[HTML][HTML] Cholinergic basal forebrain degeneration due to sleep-disordered breathing exacerbates pathology in a mouse model of Alzheimer's disease
L Qian, O Rawashdeh, L Kasas, MR Milne… - Nature …, 2022 - nature.com
Although epidemiological studies indicate that sleep-disordered breathing (SDB) such as
obstructive sleep apnea is a strong risk factor for the development of Alzheimer’s disease (AD), …
obstructive sleep apnea is a strong risk factor for the development of Alzheimer’s disease (AD), …
Assessment of the effect of a comprehensive chest radiograph deep learning model on radiologist reports and patient outcomes: a real-world observational study
CM Jones, L Danaher, MR Milne, C Tang, J Seah… - BMJ open, 2021 - bmjopen.bmj.com
Objectives Artificial intelligence (AI) algorithms have been developed to detect imaging
features on chest X-ray (CXR) with a comprehensive AI model capable of detecting 124 CXR …
features on chest X-ray (CXR) with a comprehensive AI model capable of detecting 124 CXR …
[HTML][HTML] Charting the potential of brain computed tomography deep learning systems
Brain computed tomography (CTB) scans are widely used to evaluate intracranial pathology.
The implementation and adoption of CTB has led to clinical improvements. However, …
The implementation and adoption of CTB has led to clinical improvements. However, …
Regulation of cholinergic basal forebrain development, connectivity, and function by neurotrophin receptors
Z Boskovic, S Meier, Y Wang, MR Milne… - Neuronal …, 2019 - portlandpress.com
Cholinergic basal forebrain (cBF) neurons are defined by their expression of the p75
neurotrophin receptor (p75 NTR ) and tropomyosin-related kinase (Trk) neurotrophin receptors in …
neurotrophin receptor (p75 NTR ) and tropomyosin-related kinase (Trk) neurotrophin receptors in …
[HTML][HTML] Machine learning augmented interpretation of chest X-rays: a systematic review
HK Ahmad, MR Milne, QD Buchlak, N Ektas… - Diagnostics, 2023 - mdpi.com
Limitations of the chest X-ray (CXR) have resulted in attempts to create machine learning
systems to assist clinicians and improve interpretation accuracy. An understanding of the …
systems to assist clinicians and improve interpretation accuracy. An understanding of the …
[HTML][HTML] Effect of estradiol on neurotrophin receptors in basal forebrain cholinergic neurons: Relevance for Alzheimer's disease
A Kwakowsky, MR Milne, HJ Waldvogel… - International journal of …, 2016 - mdpi.com
The basal forebrain is home to the largest population of cholinergic neurons in the brain. These
neurons are involved in a number of cognitive functions including attention, learning and …
neurons are involved in a number of cognitive functions including attention, learning and …
Removal of p75 neurotrophin receptor expression from cholinergic basal forebrain neurons reduces amyloid-β plaque deposition and cognitive impairment in aged …
…, MR Milne, S Shepheard, ML Rogers, R Medeiros… - Molecular …, 2019 - Springer
The degeneration of cholinergic basal forebrain (cBF) neurons in Alzheimer’s disease (AD)
leads to the cognitive impairment associated with this condition. cBF neurons express the …
leads to the cognitive impairment associated with this condition. cBF neurons express the …
Do comprehensive deep learning algorithms suffer from hidden stratification? A retrospective study on pneumothorax detection in chest radiography
Objectives To evaluate the ability of a commercially available comprehensive chest radiography
deep convolutional neural network (DCNN) to detect simple and tension pneumothorax, …
deep convolutional neural network (DCNN) to detect simple and tension pneumothorax, …
The p75 neurotrophin receptor is required for the survival of neuronal progenitors and normal formation of the basal forebrain, striatum, thalamus and neocortex
S Meier, F Alfonsi, ND Kurniawan, MR Milne… - …, 2019 - journals.biologists.com
During development, the p75 neurotrophin receptor (p75 NTR ) is widely expressed in the
nervous system where it regulates neuronal differentiation, migration and axonal outgrowth. …
nervous system where it regulates neuronal differentiation, migration and axonal outgrowth. …
[HTML][HTML] Effects of a comprehensive brain computed tomography deep learning model on radiologist detection accuracy
…, HK Ahmad, H Pham, JI Chiang, N Ektas, MR Milne… - European …, 2024 - Springer
Objectives Non-contrast computed tomography of the brain (NCCTB) is commonly used to
detect intracranial pathology but is subject to interpretation errors. Machine learning can …
detect intracranial pathology but is subject to interpretation errors. Machine learning can …