Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

…, H Wackerhage, PM Taylor, MJ Rennie - The FASEB …, 2005 - Wiley Online Library
The nature of the deficit underlying age‐related muscle wasting remains controversial. To test
whether it could be due to a poor anabolic response to dietary amino acids, we measured …

Acute skeletal muscle wasting in critical illness

…, LM Edwards, K Smith, A Rowlerson, MJ Rennie… - Jama, 2013 - jamanetwork.com
Importance Survivors of critical illness demonstrate skeletal muscle wasting with associated
functional impairment. Objective To perform a comprehensive prospective characterization …

Born global

MW Rennie - The McKinsey Quarterly, 1993 - go.gale.com
A study of Australian export firms has shown that many small to medium-sized companies
have been able to successfully compete with bigger and more established companies …

Age‐related differences in the dose–response relationship of muscle protein synthesis to resistance exercise in young and old men

…, O Seynnes, N Hiscock, MJ Rennie - The Journal of …, 2009 - Wiley Online Library
We investigated how myofibrillar protein synthesis (MPS) and muscle anabolic signalling were
affected by resistance exercise at 20–90% of 1 repetition maximum (1 RM) in two groups (…

Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise

…, M Kjaer, JA Babraj, K Smith, MJ Rennie - The Journal of …, 2005 - Wiley Online Library
We hypothesized that an acute bout of strenuous, non‐damaging exercise would increase
rates of protein synthesis of collagen in tendon and skeletal muscle but these would be less …

[HTML][HTML] Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial

…, BS Mohammed, D Rankin, MJ Rennie… - The American journal of …, 2011 - Elsevier
Background: Loss of muscle mass with aging is a major public health concern. Omega-3 (n–3)
fatty acids stimulate protein anabolism in animals and might therefore be useful for the …

Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle

…, MA Tarnopolsky, MJ Rennie - The journal of …, 2008 - Wiley Online Library
Resistance (RE) and endurance (EE) exercise stimulate mixed skeletal muscle protein
synthesis. The phenotypes induced by RE (myofibrillar protein accretion) and EE (mitochondrial …

[HTML][HTML] Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men

…, DR Moore, AM Holwerda, G Parise, MJ Rennie… - PloS one, 2010 - journals.plos.org
Background We aimed to determine the effect of resistance exercise intensity (% 1 repetition
maximum—1RM) and volume on muscle protein synthesis, anabolic signaling, and …

Selective activation of AMPK‐PGC‐1α or PKB‐TSC2‐mTOR signaling can explain specific adaptive responses to endurance or resistance training‐like electrical …

…, JA Babraj, K Smith, J Singh, MJ Rennie… - The FASEB …, 2005 - Wiley Online Library
Endurance training induces a partial fast‐to‐slow muscle phenotype transformation and
mitochondrial biogenesis but no growth. In contrast, resistance training mainly stimulates …

Rapid report: latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids

…, JFA Low, RR Wolfe, MJ Rennie - The Journal of …, 2001 - Wiley Online Library
1 The aim of this study was to describe the time course of the response of human muscle
protein synthesis (MPS) to a square wave increase in availability of amino acids (AAs) in …