User profiles for Michael Tscherner
Michael TschernerVerified email at univie.ac.at Cited by 791 |
[HTML][HTML] Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes
…, B Ma, E Hiller, F Istel, M Tscherner… - PLoS …, 2014 - journals.plos.org
The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis,
causing infections ranging from superficial to life-threatening disseminated disease. The …
causing infections ranging from superficial to life-threatening disseminated disease. The …
[HTML][HTML] Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata
M Tscherner, T Schwarzmüller, K Kuchler - Pharmaceuticals, 2011 - mdpi.com
Candida glabrata is a major opportunistic human fungal pathogen causing superficial as
well as systemic infections in immunocompromised individuals and several other patient …
well as systemic infections in immunocompromised individuals and several other patient …
[HTML][HTML] The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways
M Tscherner, F Zwolanek, S Jenull, FJ Sedlazeck… - PLoS …, 2015 - journals.plos.org
Human fungal pathogens like Candida albicans respond to host immune surveillance by
rapidly adapting their transcriptional programs. Chromatin assembly factors are involved in the …
rapidly adapting their transcriptional programs. Chromatin assembly factors are involved in the …
[PDF][PDF] Type I interferon response dysregulates host iron homeostasis and enhances Candida glabrata infection
M Riedelberger, P Penninger, M Tscherner, M Seifert… - Cell host & …, 2020 - cell.com
Type I interferons (IFNs-I) fulfil multiple protective functions during pathogenic infections, but
they can also cause detrimental effects and enhance immunopathology. Here, we report …
they can also cause detrimental effects and enhance immunopathology. Here, we report …
The histone acetyltransferase Hat1 facilitates DNA damage repair and morphogenesis in Candida albicans
M Tscherner, E Stappler, D Hnisz… - Molecular …, 2012 - Wiley Online Library
Chromatin assembly and remodelling is an important process during the repair of DNA damage
in eukaryotic cells. Although newly synthesized histone H 4 is acetylated prior to nuclear …
in eukaryotic cells. Although newly synthesized histone H 4 is acetylated prior to nuclear …
[HTML][HTML] The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways
Fungal virulence is regulated by a tight interplay of transcriptional control and chromatin
remodelling. Despite compelling evidence that lysine acetylation modulates virulence of …
remodelling. Despite compelling evidence that lysine acetylation modulates virulence of …
[HTML][HTML] Transcriptome Signatures Predict Phenotypic Variations of Candida auris
S Jenull, M Tscherner, N Kashko… - Frontiers in cellular …, 2021 - frontiersin.org
Health care facilities are facing serious threats by the recently emerging human fungal
pathogen Candida auris owing to its pronounced antifungal multidrug resistance and poor …
pathogen Candida auris owing to its pronounced antifungal multidrug resistance and poor …
[PDF][PDF] The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence
S Jenull, T Mair, M Tscherner, P Penninger… - Cell reports, 2021 - cell.com
Adaptation to changing environments and immune evasion is pivotal for fitness of pathogens.
Yet, the underlying mechanisms remain largely unknown. Adaptation is governed by …
Yet, the underlying mechanisms remain largely unknown. Adaptation is governed by …
A Synthetic System That Senses Candida albicans and Inhibits Virulence Factors
Due to a limited set of antifungals available and problems in early diagnosis, invasive
fungal infections caused by Candida species are among the most common hospital-acquired …
fungal infections caused by Candida species are among the most common hospital-acquired …
[PDF][PDF] The YEATS domain histone crotonylation readers control virulence-related biology of a major human pathogen
…, M See, A Swaminathan, K Kuchler, M Tscherner… - Cell reports, 2020 - cell.com
Identification of multiple histone acylations diversifies transcriptional control by metabolism,
but their functions are incompletely defined. Here we report evidence of histone crotonylation …
but their functions are incompletely defined. Here we report evidence of histone crotonylation …