User profiles for Michalis Barkoulas
Michalis BarkoulasImperial College London Verified email at imperial.ac.uk Cited by 3035 |
Control of leaf and vein development by auxin
E Scarpella, M Barkoulas… - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Leaves are the main photosynthetic organs of vascular plants and show considerable
diversity in their geometries, ranging from simple spoonlike forms to complex shapes with …
diversity in their geometries, ranging from simple spoonlike forms to complex shapes with …
Pervasive robustness in biological systems
MA Félix, M Barkoulas - Nature Reviews Genetics, 2015 - nature.com
Robustness is characterized by the invariant expression of a phenotype in the face of a genetic
and/or environmental perturbation. Although phenotypic variance is a central measure in …
and/or environmental perturbation. Although phenotypic variance is a central measure in …
From genes to shape: regulatory interactions in leaf development
M Barkoulas, C Galinha, SP Grigg, M Tsiantis - Current opinion in plant …, 2007 - Elsevier
In the past two years novel connections were described between auxin function and
transcription factor patterning systems involved in both leaf initiation and elaboration of leaf axial …
transcription factor patterning systems involved in both leaf initiation and elaboration of leaf axial …
Model for the regulation of Arabidopsis thaliana leaf margin development
…, A Runions, M Barkoulas… - Proceedings of the …, 2011 - National Acad Sciences
Biological shapes are often produced by the iterative generation of repeated units. The
mechanistic basis of such iteration is an area of intense investigation. Leaf development in the …
mechanistic basis of such iteration is an area of intense investigation. Leaf development in the …
ASYMMETRIC LEAVES1 and auxin activities converge to repress BREVIPEDICELLUS expression and promote leaf development in Arabidopsis
Leaf development in higher plants requires the specification of leaf initials at the flanks of a
pluripotent structure termed the shoot apical meristem. In Arabidopsis, this process is …
pluripotent structure termed the shoot apical meristem. In Arabidopsis, this process is …
A developmental framework for dissected leaf formation in the Arabidopsis relative Cardamine hirsuta
The developmental basis for the generation of divergent leaf forms is largely unknown. Here
we investigate this problem by studying processes that distinguish development of two …
we investigate this problem by studying processes that distinguish development of two …
[HTML][HTML] Invasive cell fate requires G1 cell-cycle arrest and histone deacetylase-mediated changes in gene expression
Despite critical roles in development and cancer, the mechanisms that specify invasive
cellular behavior are poorly understood. Through a screen of transcription factors in …
cellular behavior are poorly understood. Through a screen of transcription factors in …
[PDF][PDF] Arabidopsis PLETHORA transcription factors control phyllotaxis
The pattern of plant organ initiation at the shoot apical meristem (SAM), termed phyllotaxis,
displays regularities that have long intrigued botanists and mathematicians alike. In the SAM, …
displays regularities that have long intrigued botanists and mathematicians alike. In the SAM, …
Cardamine hirsuta: a versatile genetic system for comparative studies
…, RD Ioio, SJ McGowan, M Barkoulas… - The Plant …, 2014 - Wiley Online Library
A major goal in biology is to identify the genetic basis for phenotypic diversity. This goal
underpins research in areas as diverse as evolutionary biology, plant breeding and human …
underpins research in areas as diverse as evolutionary biology, plant breeding and human …
[HTML][HTML] Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans
Immune genes are under intense, pathogen-induced pressure, which causes these genes
to diversify over evolutionary time and become species-specific. Through a forward genetic …
to diversify over evolutionary time and become species-specific. Through a forward genetic …