Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria
…, K Sotlar, AW Hauswirth, M Arock… - European journal of …, 2007 - Wiley Online Library
Although a classification for mastocytosis and diagnostic criteria are available, there remains
a need to define standards for the application of diagnostic tests, clinical evaluations, and …
a need to define standards for the application of diagnostic tests, clinical evaluations, and …
Cancer stem cell definitions and terminology: the devil is in the details
…, A Roesch, GJ Schuurhuis, S Wöhrer, M Arock… - Nature Reviews …, 2012 - nature.com
The cancer stem cell (CSC) concept has important therapeutic implications, but its investigation
has been hampered both by a lack of consistency in the terms used for these cells and …
has been hampered both by a lack of consistency in the terms used for these cells and …
Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal
P Valent, C Akin, M Arock, K Brockow… - International archives of …, 2012 - karger.com
Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various
organs are typically found in primary MC disorders also referred to as mastocytosis. …
organs are typically found in primary MC disorders also referred to as mastocytosis. …
Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes
…, G Metzgeroth, KM Leiferman, M Arock… - Journal of Allergy and …, 2012 - Elsevier
Eosinophilia is an important indicator of various neoplastic and nonneoplastic conditions.
Depending on the underlying disease and mechanisms, eosinophil infiltration can lead to …
Depending on the underlying disease and mechanisms, eosinophil infiltration can lead to …
Toll‐like receptor 2 (TLR2) and TLR4 differentially activate human mast cells
…, NB Hamouda, JM Pleau, M Dy, M Arock - European journal of …, 2003 - Wiley Online Library
In the present report we have analyzed whether human normal cord blood‐derived mast
cells (CBMC) could interact with bacterial products, especially lipopolysaccharide (LPS) from …
cells (CBMC) could interact with bacterial products, especially lipopolysaccharide (LPS) from …
[HTML][HTML] Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
Background The stem cell factor receptor, KIT, is a target for the treatment of cancer,
mastocytosis, and inflammatory diseases. Here, we characterise the in vitro and in vivo profiles of …
mastocytosis, and inflammatory diseases. Here, we characterise the in vitro and in vivo profiles of …
[HTML][HTML] Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations
…, JM Launay, S Barete, F Feger, M Arock… - Journal of Investigative …, 2010 - Elsevier
Adult mastocytosis is an incurable clonal disease associated with c-KIT mutations, mostly in
exon 17 (D 816 V). In contrast, pediatric mastocytosis often spontaneously regresses and is …
exon 17 (D 816 V). In contrast, pediatric mastocytosis often spontaneously regresses and is …
Cutaneous manifestations in patients with mastocytosis: consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy …
Cutaneous lesions in patients with mastocytosis are highly heterogeneous and encompass
localized and disseminated forms. Although a classification and criteria for cutaneous …
localized and disseminated forms. Although a classification and criteria for cutaneous …
Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.
Allergic symptoms result from the release of granular and lipidic mediators and of cytokines
by inflammatory cells. The whole process is initiated by the aggregation of mast cell and …
by inflammatory cells. The whole process is initiated by the aggregation of mast cell and …
[HTML][HTML] Updated diagnostic criteria and classification of mast cell disorders: a consensus proposal
…, LB Schwartz, A Reiter, A Orfao, J Gotlib, M Arock… - …, 2021 - journals.lww.com
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation
of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), …
of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), …