[HTML][HTML] Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

…, WN Dobson-Belaire, M Ouellet, MJ Tremblay… - PLoS …, 2010 - journals.plos.org
While several clinical studies have shown that HIV-1 infection is associated with increased
permeability of the intestinal tract, there is very little understanding of the mechanisms …

Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element

…, MÈ Janelle, L Flamand, MJ Tremblay… - Nucleic acids …, 2008 - academic.oup.com
The interaction between human immunodeficiency virus type 1 (HIV-1) and RNA silencing
pathways is complex and multifaceted. Essential for efficient viral transcription and supporting …

Plunder and stowaways: incorporation of cellular proteins by enveloped viruses

R Cantin, S Méthot, MJ Tremblay - Journal of virology, 2005 - Am Soc Microbiol
To be successful and have the opportunity to replicate properly, a virus has to thwart or, just
the reverse, boost many systems of the host cell. Given that host cells have evolved to …

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

…, M Richard, AD Beaulieu, MJ Tremblay - Blood, The Journal …, 2008 - ashpublications.org
The dynamic interplay between dendritic cells (DCs) and human immunodeficiency virus
type-1 (HIV-1) is thought to result in viral dissemination and evasion of antiviral immunity. …

Galectin-1 acts as a soluble host factor that promotes HIV-1 infectivity through stabilization of virus attachment to host cells

…, J Roy, J Hirabayashi, S Sato, MJ Tremblay - The Journal of …, 2005 - journals.aai.org
The establishment of HIV type 1 (HIV-1) infection is initiated by the stable attachment of the
virion to the target cell surface. Although this process relies primarily upon interaction …

[HTML][HTML] Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy

…, S Boisvert, P Rigault, J Corbeil, MJ Tremblay… - Genome biology, 2008 - Springer
Background Drug resistance can be complex, and several mutations responsible for it can
co-exist in a resistant cell. Transcriptional profiling is ideally suited for studying complex …

The acquisition of host-encoded proteins by nascent HIV-1

MJ Tremblay, JF Fortin, R Cantin - Immunology today, 1998 - cell.com
The human immunodeficiency virus type 1 (HIV-1) incorporates several host-derived proteins
during the budding process. Here, Michel Tremblay and colleagues review recent studies …

Presence of Host ICAM-1 in Laboratory and Clinical Strains of Human Immunodeficiency Virus Type 1 Increases Virus Infectivity and CD4+-T-Cell Depletion in …

S Bounou, JE Leclerc, MJ Tremblay - Journal of virology, 2002 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) incorporates several host proteins. Earlier
studies have indicated that such foreign constituents can modulate the virus life cycle, although …

Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species

…, A Isnard, M Stanke, M Olivier, MJ Tremblay… - Nucleic acids …, 2012 - academic.oup.com
The Leishmania tarentolae Parrot-TarII strain genome sequence was resolved to an average
16-fold mean coverage by next-generation DNA sequencing technologies. This is the first …

HIV-1 gp120 induces TLR2-and TLR4-mediated innate immune activation in human female genital epithelium

…, MF Mian, M Ouellet, MJ Tremblay… - The Journal of …, 2013 - journals.aai.org
Although women constitute half of all HIV-1–infected people worldwide (UNAIDS World
AIDS Day Report, 2011), the earliest events in the female reproductive tract (FRT) during …