Ovarian cancer is a highly metastatic disease and the leading cause of death from
gynecologic malignancy. Hence, and understanding of the molecular changes associated with …

… -Michel Boisvert was supported by an operating grant from the Canadian Institutes for
Health Research (MOP-123469). Work in Michel Salzet's … support (to Dr Salzet's laboratory). …

Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive
molecular analyses of GBM cells. In recent years, the tumor microenvironment (TME) has been …

Many neuropeptides and peptide hormones are very similar to antimicrobial peptides in their
amino acid composition, amphipathic design, cationic charge and size. Their antimicrobial …

Four cationic peptides were purified from mussel (Mytilus galloprovincialis) hemocytes. A
combination of Edman degradation and mass spectrometry of plasma revealed (i) a previously …

An expensive group of cationic antimicrobial peptides has been isolated from animals and
plants during the past two decades. Three novel classes of natural antibiotics (anionic …

Cannabinoid receptors and their endogenous ligands, the endocannabinoids, have been
detected in several blood immune cells, including monocytes/macrophages, basophils and …

MALDI imaging mass spectrometry represents a new analytical tool to directly provide the
spatial distribution and relative abundance of proteins in tissue. Twenty-five ovary carcinomas (…

A decade after its inception, MALDI imaging mass spectrometry has become a unique technique
in the proteomics arsenal for biomarker hunting in a variety of diseases. At this stage of …

Research on the innate immune response of mammals has revealed similarities with the
invertebrate immune system. Thus, insects have developed an acute response resembling that …