An interferon‐γ‐related cytokine storm in SARS patients
KJ Huang, IJ Su, M Theron, YC Wu… - Journal of medical …, 2005 - Wiley Online Library
Fourteen cytokines or chemokines were analyzed on 88 RT‐PCR‐confirmed severe acute
respiratory syndrome (SARS) patients. IFN‐γ, IL‐18, TGF‐β, IL‐6, IP‐10, MCP‐1, MIG, and IL‐…
respiratory syndrome (SARS) patients. IFN‐γ, IL‐18, TGF‐β, IL‐6, IP‐10, MCP‐1, MIG, and IL‐…
Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum
…, LY Bustamante, SJ Bartholdson, AK Bei, M Theron… - Nature, 2011 - nature.com
Erythrocyte invasion by Plasmodium falciparum is central to the pathogenesis of malaria.
Invasion requires a series of extracellular recognition events between erythrocyte receptors …
Invasion requires a series of extracellular recognition events between erythrocyte receptors …
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
…, P Vauterin, R Pearson, S Campino, M Theron… - Genome …, 2016 - genome.cshlp.org
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary adaptation
to evade host immunity and develop drug resistance. Current understanding of parasite …
to evade host immunity and develop drug resistance. Current understanding of parasite …
Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5
…, DK Awuah, DGW Alanine, M Theron… - The Journal of …, 2014 - journals.aai.org
There is intense interest in induction and characterization of strain-transcending neutralizing
Ab against antigenically variable human pathogens. We have recently identified the human …
Ab against antigenically variable human pathogens. We have recently identified the human …
[HTML][HTML] Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors
AA Lamikanra, M Theron, TWA Kooij, DJ Roberts - PloS one, 2009 - journals.plos.org
Severe malarial anemia is the most common syndrome of severe malaria in endemic areas.
The pathophysiology of chronic malaria is characterised by a striking degree of abnormal …
The pathophysiology of chronic malaria is characterised by a striking degree of abnormal …
[HTML][HTML] Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts
…, S Assouline, M Hashemyan, M Theron… - …, 2016 - ncbi.nlm.nih.gov
CD34+/CD45dim/CD117+ 0.00018 0.74 [0.63, 0.86] 0.00054 0.74 [0.61, 0.87] first part of
study NP28679. Eighty-nine patients with AML were treated with idasanutlin-based therapy, …
study NP28679. Eighty-nine patients with AML were treated with idasanutlin-based therapy, …
[PDF][PDF] Quantitation of malaria parasite-erythrocyte cell-cell interactions using optical tweezers
Erythrocyte invasion by Plasmodium falciparum merozoites is an essential step for parasite
survival and hence the pathogenesis of malaria. Invasion has been studied intensively, but …
survival and hence the pathogenesis of malaria. Invasion has been studied intensively, but …
A probable role for IFN-γ in the development of a lung immunopathology in SARS
M Theron, KJ Huang, YW Chen, CC Liu, HY Lei - Cytokine, 2005 - Elsevier
Recent work carried out in our laboratory showed the existence of a cytokine storm in SARS
patients, dominated by Th1-type mediators. We thus hypothesized that IFN-γ may play a …
patients, dominated by Th1-type mediators. We thus hypothesized that IFN-γ may play a …
An adaptable two‐color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites
M Theron, RL Hesketh, S Subramanian… - Cytometry Part …, 2010 - Wiley Online Library
Plasmodium falciparum genotyping has recently undergone a revolution, and genome‐wide
genotype datasets are now being collected for large numbers of parasite isolates. By …
genotype datasets are now being collected for large numbers of parasite isolates. By …
[HTML][HTML] Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model
…, N Ruderisch, V Costa, FC Weber, M Theron… - Genome medicine, 2016 - Springer
Background Tuberous sclerosis complex (TSC) is a genetic disease characterized by
benign tumor growths in multiple organs and neurological symptoms induced by mTOR …
benign tumor growths in multiple organs and neurological symptoms induced by mTOR …