User profiles for Michelle D. Failla

Michelle D. Failla

The Ohio State University
Verified email at osu.edu
Cited by 1833

S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury

A Goyal, MD Failla, C Niyonkuru, K Amin… - Journal of …, 2013 - liebertpub.com
As an astrocytic protein specific to the central nervous system, S100b is a potentially useful
marker in outcome prediction after traumatic brain injury (TBI). Some studies have …

IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

ML Diamond, AC Ritter, MD Failla, JA Boles… - …, 2014 - Wiley Online Library
Objective Posttraumatic epilepsy ( PTE ) is a significant complication following traumatic
brain injury ( TBI ), yet the role of genetic variation in modulating PTE onset is unclear. We …

Initially intact neural responses to pain in autism are diminished during sustained pain

MD Failla, EJ Moana-Filho, GK Essick, GT Baranek… - …, 2018 - journals.sagepub.com
Pain assessments typically depend on self-report of the pain experience. Yet, in individuals
with autism spectrum disorders, this can be an unreliable due to communication difficulties. …

Brain-Derived Neurotrophic Factor (BDNF) in traumatic brain injury–related mortality: interrelationships between genetics and acute systemic and central nervous …

MD Failla, YP Conley… - … and neural repair, 2016 - journals.sagepub.com
Background. Older adults have higher mortality rates after severe traumatic brain injury (TBI)
compared to younger adults. Brain-derived neurotrophic factor (BDNF) signaling is altered …

[HTML][HTML] Intrainsular connectivity and somatosensory responsiveness in young children with ASD

MD Failla, BR Peters, H Karbasforoushan… - Molecular Autism, 2017 - Springer
Background The human somatosensory system comprises dissociable paths for discriminative
and affective touch, reflected in separate peripheral afferent populations and distinct …

Acute inflammatory biomarker profiles predict depression risk following moderate to severe traumatic brain injury

SB Juengst, RG Kumar, MD Failla… - The Journal of head …, 2015 - journals.lww.com
Objective: To examine whether acute inflammation profiles predict posttraumatic depression
(PTD) risk 6 and 12 months after traumatic brain injury. Setting: University-affiliated level 1 …

Variation in the BDNF gene interacts with age to predict mortality in a prospective, longitudinal cohort with severe TBI

MD Failla, RG Kumar, AB Peitzman… - … and Neural Repair, 2015 - journals.sagepub.com
Background. Mortality predictions following traumatic brain injury (TBI), and our understanding
of TBI pathology, may be improved by including genetic risk in addition to traditional …

[HTML][HTML] Increased pain sensitivity and pain-related anxiety in individuals with autism

MD Failla, MB Gerdes, ZJ Williams, DJ Moore… - Pain …, 2020 - journals.lww.com
Objectives: We hypothesized that individuals with ASD would report increased pain
sensitivity and endorse more pain-related anxiety, compared to typically developing controls. …

Psychometric evaluation of the short sensory profile in youth with autism spectrum disorder

ZJ Williams, MD Failla, KO Gotham… - Journal of autism and …, 2018 - Springer
The Short Sensory Profile (SSP) is one of the most commonly used measures of sensory
features in children with autism spectrum disorder (ASD), but psychometric studies in this …

Preliminary associations between brain-derived neurotrophic factor, memory impairment, functional cognition, and depressive symptoms following severe TBI

MD Failla, SB Juengst, PM Arenth… - … and neural repair, 2016 - journals.sagepub.com
Background. Traumatic brain injury (TBI) often leads to mood and cognitive complications,
affecting functional recovery. Understanding neurobiological alterations common in post-TBI …