Cancer is the second most common cause of death in developed countries with approximately
14 million newly diagnosed individuals and over 6 million cancer-related deaths in 2012. …

Carbohydrates participate in almost every aspect of biology from protein sorting to modulating
cell differentiation and cell–cell interactions. To date, the majority of data gathered on …

Microtiter plate colorimetric assays are widely used for analysis of carbohydrates and
glycoconjugates. However, mucins are often not easily detected, as they have low neutral sugar …

Background Bifidobacteria constitute a specific group of commensal bacteria that commonly
inhabit the mammalian gastrointestinal tract. Bifidobacterium breve UCC2003 was …

Six polysaccharides were extracted sequentially from the fresh sclerotium of Poria cocos
cultivated in China using 0.9% NaCl (PCS1), hot water (PCS2), 0.5M NaOH (PCS3-I and PCS3-…

Ischemic heart disease is a leading cause of mortality due to irreversible damage to cardiac
muscle. Inspired by the post-ischemic microenvironment, we devised an extracellular matrix (…

Painful intervertebral disc degeneration is mediated by inflammation that modulates
glycosylation and induces hyperinnervation and sensory sensitization, which result in discogenic …

Tendon disease constitutes an unmet clinical need and remains a critical challenge in the
field of orthopaedic surgery. Innovative solutions are required to overcome the limitations of …

Helminth parasites secrete extracellular vesicles (EVs) that can be internalised by host
immune cells resulting in modulation of host immunity. While the molecular cargo of EVs have …

Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system
that are critical to maintaining the long-term relationship between parasite and host. In the …