Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation
…, Y Liu, MT Muldowney… - Proceedings of the …, 2012 - National Acad Sciences
Suppressor of cytokine signaling (SOCS) proteins are feedback inhibitors of the JAK/STAT
pathway. SOCS3 has a crucial role in inhibiting STAT3 activation, cytokine signaling, and …
pathway. SOCS3 has a crucial role in inhibiting STAT3 activation, cytokine signaling, and …
Suppressor of cytokine signaling 3 inhibits antiviral IFN-β signaling to enhance HIV-1 replication in macrophages
LN Akhtar, H Qin, MT Muldowney… - The Journal of …, 2010 - journals.aai.org
HIV-1 replication within macrophages of the CNS often results in cognitive and motor
impairment, which is known as HIV-associated dementia (HAD) in its most severe form. IFN-β …
impairment, which is known as HIV-associated dementia (HAD) in its most severe form. IFN-β …
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity
SN Kudalkar, OJ Njuma, Y Li, M Muldowney… - Biochemistry, 2015 - ACS Publications
Catalase-peroxidases (KatGs), the only catalase-active members of their superfamily, all
possess a 35-residue interhelical loop called large loop 2 (LL2). It is essential for catalase …
possess a 35-residue interhelical loop called large loop 2 (LL2). It is essential for catalase …
Lysosomal enzyme tripeptidyl peptidase 1 plays a role in degradation of beta amyloid fibrils
…, M El-Banna, A Majumdar, DE Sleat, M Muldowney… - BioRxiv, 2019 - biorxiv.org
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid plaques surrounded
by microglia. In cell culture, microglia internalize fibrillar β-amyloid but do not degrade it …
by microglia. In cell culture, microglia internalize fibrillar β-amyloid but do not degrade it …
Critical function of myeloid SOCS3 is in limiting the neuroinflammation of EAE (147.21)
Macrophages and microglia are central players in the pathogenesis of inflammatory diseases
in the CNS, such as Multiple Sclerosis. SOCS proteins are critical feedback inhibitors of …
in the CNS, such as Multiple Sclerosis. SOCS proteins are critical feedback inhibitors of …
[BOOK][B] Examining the role of the lysosomal enzyme tripeptidyl-peptidase I in the degradation of fibrillar beta-amyloid
DL Cruz - 2013 - search.proquest.com
… Amitabha Majumdar for his collaboration and for training me on the Alzheimer's Disease
project; the laboratory technicians, Michelle Muldowney, Adina Buxbaum and Nikiya Asamoah, …
project; the laboratory technicians, Michelle Muldowney, Adina Buxbaum and Nikiya Asamoah, …
Informal carer support needs, facilitators and barriers in transitional care for older adults from hospital to home: A scoping review
…, M Lobchuk, A Muldowney… - Journal of Clinical …, 2023 - Wiley Online Library
Aim To synthesise evidence about informal carers' (carers) experience of their support
needs, facilitators and barriers regarding transitional care of older adults with multimorbidity. …
needs, facilitators and barriers regarding transitional care of older adults with multimorbidity. …
[PDF][PDF] Perioperative Outcomes and Surgical Case Volume in Pediatric Complex Cranial Vault Reconstruction: A Multicenter Observational Study From the Pediatric …
BL Muldowney, JL Martinez, F Chiao, PA Stricker - 2018 - academia.edu
BACKGROUND: Complex cranial vault reconstruction (CCVR) performed to treat
craniosynostosis can be associated with significant blood loss, transfusion, and perioperative …
craniosynostosis can be associated with significant blood loss, transfusion, and perioperative …
[PDF][PDF] Outward Beauty, Hidden Wrath: An Exploration of the Drikung Kagyü Dharma Protectress Achi Chökyi Drölma
KK Muldowney - 2011 - diginole.lib.fsu.edu
… The members of the committee approve the thesis of Kristen Kail Muldowney defended on …
of Buddhism,” in Du Dunhuang au Japon: Études chinoises et bouddhiques offertes à Michel …
of Buddhism,” in Du Dunhuang au Japon: Études chinoises et bouddhiques offertes à Michel …
'A world of its own': recollections of women workers in Guinness's brewery in the 1940s
M Muldowney - Saothar, 1998 - JSTOR
During the 1940s, despite the reduction in many areas of work occasioned by the Emergency,
the Guinness brewery in St James's Gate provided secure employment for a wide range of …
the Guinness brewery in St James's Gate provided secure employment for a wide range of …