[HTML][HTML] Genetic disease risks can be misestimated across global populations

MS Kim, KP Patel, AK Teng, AJ Berens, J Lachance - Genome biology, 2018 - Springer
Background Accurate assessment of health disparities requires unbiased knowledge of
genetic risks in different populations. Unfortunately, most genome-wide association studies use …

Early use of high-dose glucocorticoid for the management of irAE is associated with poorer survival in patients with advanced melanoma treated with anti–PD-1 …

…, L Pallan, C Harvey, MP Manos, O Ouyang, MS Kim… - Clinical cancer …, 2021 - AACR
Purpose: Programmed cell death receptor-1 (PD-1) inhibitors are frontline therapy in
advanced melanoma. Severe immune-related adverse effects (irAEs) often require …

The Warrington Recognition Memory Test for Words as a measure of response bias: Total score and response time cutoffs developed on “real world” credible and …

MS Kim, KB Boone, T Victor, SD Marion… - Archives of Clinical …, 2010 - academic.oup.com
Several studies have examined the usefulness of the Warrington Recognition Memory Test–Words
as a measure to detect suspect effort, although samples have generally been small …

Medication and finance management among HIV-infected adults: the impact of age and cognition

AD Thames, MS Kim, BW Becker, JM Foley… - Journal of clinical and …, 2011 - Taylor & Francis
This study examined the effects of aging and cognitive impairment on medication and finance
management in an HIV sample. We observed main effects of age (older < younger) and …

The effect of intranasal fentanyl on the emergence characteristics after sevoflurane anesthesia in children undergoing surgery for bilateral myringotomy tube …

…, IT Cohen, RS Hannallah, KM Patel, MS Kim… - Anesthesia & …, 2001 - journals.lww.com
IMPLICATIONS: We examined the use of nasally administered fentanyl for the relief of agitation
or discomfort after placement of bilateral myringotomy tubes in 150 children ages 6 mo to …

Incidence of postconcussion symptoms in psychiatric diagnostic groups, mild traumatic brain injury, and comorbid conditions

AJ Donnell, MS Kim, MA Silva… - The Clinical …, 2012 - Taylor & Francis
The constellation of physical, cognitive, and emotional symptoms, collectively known as
postconcussion syndrome (PCS), is not uniquely associated with concussion, making the …

Cognitive reserve as a protective factor in older HIV-positive patients at risk for cognitive decline

…, MS Kim, N Behdin, SA Castellon… - Applied …, 2012 - Taylor & Francis
The present study examined the impact of cognitive reserve in maintaining intact
neuropsychological (NP) function among older HIV-positive individuals, a uniquely at-risk subgroup. …

ATP stimulates pannexin 1 internalization to endosomal compartments

AKJ Boyce, MS Kim, LE Wicki-Stordeur… - Biochemical …, 2015 - portlandpress.com
The ubiquitous pannexin 1 (Panx1) ion- and metabolite-permeable channel mediates the
release of ATP, a potent signalling molecule. In the present study, we provide striking evidence …

[HTML][HTML] Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa

MS Kim, D Naidoo, U Hazra, MH Quiver, WC Chen… - Genome biology, 2022 - Springer
Background Genome-wide association studies do not always replicate well across populations,
limiting the generalizability of polygenic risk scores (PRS). Despite higher incidence and …

Benefit and toxicity of programmed death‐1 blockade vary by ethnicity in patients with advanced melanoma: an international multicentre observational study

…, MZ Zhang, L Pallan, C Harvey, MS Kim… - British Journal of …, 2022 - academic.oup.com
Background Programmed cell death receptor‐1 (PD‐1) monotherapy is a standard treatment
for advanced cutaneous melanoma, but its efficacy and toxicity are defined in white …