Soluble amyloid-beta (Aβ) aggregates likely contribute substantially to the dementia that
characterizes Alzheimer’s disease. However, despite intensive study of in vitro preparations …

Chronic traumatic encephalopathy (CTE) is a progressive degenerative disorder associated
with repetitive traumatic brain injury. One of the primary defining neuropathological lesions …

The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with
repeated head traumas. Using immunohistochemistry for glial fibrillary acidic protein as a …

Purpose Pluronic has been shown to sensitize various tumor cell lines to chemotherapy and
hyperthermia by altering the membrane fluidity, depleting ATP, and modulating the heat …

The brain's complex microconnectivity underlies its computational abilities and vulnerability
to injury and disease. It has been challenging to illuminate the features of this synaptic …

Advanced diffusion MRI methods have recently been proposed for detection of pathologies
such as traumatic axonal injury and chronic traumatic encephalopathy which commonly …

Due to the unmet need for a means to study chronic traumatic encephalopathy (CTE) in vivo,
there have been numerous efforts to develop an animal model of this progressive tauopathy…

Background: Hepatocellular carcinomas are frequently nonresponsive to systemically delivered
drugs. Local delivery provides an alternative to systemic administration, maximizing the …

Cognitive deficits are among the most severe and pervasive consequences of aneurysmal
subarachnoid hemorrhage (SAH). A critical step in developing therapies targeting such …