Glycerol-3-phosphate (G3P) is an important metabolite that contributes to the growth and
disease-related physiologies of prokaryotes, plants, animals and humans alike. Here we show …

Systemic acquired resistance (SAR), a highly desirable form of plant defense, provides
broad-spectrum immunity against diverse pathogens. The recent identification of seemingly …

Resistance (R) protein–associated pathways are well known to participate in defense
against a variety of microbial pathogens. Salicylic acid (SA) and its associated proteinaceous …

The conserved cellular metabolites nitric oxide ( NO ) and oleic acid ( 18:1 ) are well-known
regulators of disease physiologies in diverse organism. We show that NO production in …

Since the 1950s, research on the animal neurohormone, melatonin, has focused on its
multiregulatory effect on patients suffering from insomnia, cancer, and Alzheimer’s disease. In …

The widespread emergence of methicillin-resistant Staphylococcus aureus (MRSA) has
dramatically eroded the efficacy of current β-lactam antibiotics and created an urgent need for …

Plant viruses cause enormous losses in agricultural production accounting for about 47% of
the total overall crop losses caused by plant pathogens. More than 50% of the emerging …

American chestnut was once a foundation species of eastern North American forests, but
was rendered functionally extinct in the early 20th century by an exotic fungal blight (…

Inositol pyrophosphates are unique cellular signaling molecules with recently discovered
roles in energy sensing and metabolism. Studies in eukaryotes have revealed that these …

Background The ultimate phenome of any organism is modulated by regulated transcription
of many genes. Characterization of genetic makeup is thus crucial for understanding the …