[HTML][HTML] Multi-omics reveals mitochondrial metabolism proteins susceptible for drug discovery in AML
M Caplan, KJ Wittorf, KK Weber, SA Swenson… - Leukemia, 2022 - nature.com
Acute myeloid leukemia (AML) is a devastating cancer affecting the hematopoietic system.
Previous research has relied on RNA sequencing and microarray techniques to study the …
Previous research has relied on RNA sequencing and microarray techniques to study the …
[HTML][HTML] Loss of FBXO9 enhances proteasome activity and promotes aggressiveness in acute myeloid leukemia
…, SA Swenson, H Vahle, KJ Wittorf, M Caplan… - Cancers, 2019 - mdpi.com
The hematopoietic system is maintained throughout life by stem cells that are capable of
differentiating into all hematopoietic lineages. An intimate balance between self-renewal, …
differentiating into all hematopoietic lineages. An intimate balance between self-renewal, …
Ubiquitin E3 ligase FBXO9 regulates pluripotency by targeting DPPA5 for ubiquitylation and degradation
…, C Bea Winship, R Willow Hynes-Smith, M Caplan… - Stem Cells, 2024 - academic.oup.com
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have unique
characteristics where they can both contribute to all three germ layers in vivo and self-renewal …
characteristics where they can both contribute to all three germ layers in vivo and self-renewal …
Regulation of GPCR‐induced Hippo pathway signaling by ARRDC3 in breast carcinoma
M Caplan, JA Trejo - The FASEB Journal, 2022 - Wiley Online Library
G protein‐coupled receptors (GPCRs) are a large and diverse family of cell surface receptors
implicated in cancer progression. In particular, overexpression of the GPCR protease‐…
implicated in cancer progression. In particular, overexpression of the GPCR protease‐…
Identifying protein expression changes in acute myeloid leukemia
M Caplan, W Hynes-Smith, S Swenson… - The FASEB …, 2020 - Wiley Online Library
Acute myeloid leukemia (AML) is a devastating cancer affecting the hematopoietic system. It
is characterized by infiltration of abnormal proliferating immature myeloid cells originating in …
is characterized by infiltration of abnormal proliferating immature myeloid cells originating in …
HIV Suppresses Cervical Neutrophil Infiltration in Women with Normal or Abnormal Pap Smears
Human immunodeficiency virus (HIV) infection of CD4+ T cells results in a weakened
immune system due to decreased white blood cells, particularly multi-lobed neutrophils (…
immune system due to decreased white blood cells, particularly multi-lobed neutrophils (…
The role of E3 ubiquitin ligase FBXO9 in normal and malignant hematopoiesis
R Hynes-Smith - 2019 - digitalcommons.unmc.edu
… Samantha Swenson, Karli Wittorf, Tyler Gilbreath, and Mika Caplan. Thank you for sharing
your knowledge with me and helping me at times when I was unable to complete projects, …
your knowledge with me and helping me at times when I was unable to complete projects, …
[HTML][HTML] mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft
D Magda, P Lecane, J Prescott, P Thiemann, X Ma… - BMC genomics, 2008 - Springer
Background Interactions between the gene products encoded by the mitochondrial and
nuclear genomes play critical roles in eukaryotic cellular function. However, the effects …
nuclear genomes play critical roles in eukaryotic cellular function. However, the effects …
The cytoskeleton‐associated TCR ζ chain is constitutively phosphorylated in the absence of an active p56lck form
S Caplan, O Almogi‐Hazan, A Ezernitchi… - European Journal of …, 2001 - Wiley Online Library
… We also thank Mika Caplan for her efforts on our behalf. We gratefully acknowledge the
support of the Society for Research Associates of the Lautenberg Center, the United States-…
support of the Society for Research Associates of the Lautenberg Center, the United States-…
Neutrophil Infiltration into the Cervical Compartment is Suppressed by HIV Infection
M Maschka - 2020 - digitalcommons.unl.edu
Human Papillomavirus (HPV), is a small circular dsDNA virus with at least 200 different
genotypes; each genotype is identified by at least 10% difference at the DNA level in the L1 …
genotypes; each genotype is identified by at least 10% difference at the DNA level in the L1 …