Arecoline is a naturally occurring psychoactive alkaloid with partial agonism at nicotinic and
muscarinic acetylcholine receptors. Arecoline consumption is widespread, making it the …

Trace amines are structurally close to classical monoamine neurotransmitters and can play
an important role in regulating brain functions. Trace amine-associated receptors(TAARs) …

Stress-related neuropsychiatric disorders are widespread, debilitating and often treatment-resistant
illnesses that represent an urgent unmet biomedical problem. Animal models of …

Background Affective disorders, especially depression and anxiety, are highly prevalent,
debilitating mental illnesses. Animal experimental models are a valuable tool in translational …

Parkinson’s disease is the second most common neurodegenerative pathology. Due to the
limitations of existing therapeutic approaches, novel anti-parkinsonian medicines with non-…

Long-term recurrent stress is a common cause of neuropsychiatric disorders. Animal models
are widely used to study the pathogenesis of stress-related psychiatric disorders. The …

Hallucinogenic drugs potently affect brain and behavior and have also recently emerged as
potentially promising agents in pharmacotherapy. Complementing laboratory rodents, the …

Elaboration of protocols for differentiation of human pluripotent stem cells to dopamine neurons
is an important issue for development of cell replacement therapy for Parkinson’s disease…

Serotonergic hallucinogenic drugs potently affect human brain and behavior, and have
recently emerged as potentially promising agents in psychopharmacotherapy. Complementing …

Long-term recurrent stress is a common cause of neuropsychiatric disorders. Animal models
are widely used to study the pathogenesis of stress-related psychiatric disorders. The …