Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity
…, S Ohkubo, K Endoh, M Kato… - Proceedings of the …, 2013 - National Acad Sciences
GATA binding protein 3 (Gata3) is a GATA family transcription factor that controls differentiation
of naïve CD4 T cells into T helper 2 (Th2) cells. However, it is unknown how Gata3 …
of naïve CD4 T cells into T helper 2 (Th2) cells. However, it is unknown how Gata3 …
Analysis of Antioxidant Activities Contained in the Boesenbergia pandurata Schult. Rhizome
K Shindo, M Kato, A Kinoshita… - Bioscience …, 2006 - academic.oup.com
The rhizome of Boesenbergia pandurata Schult. was found to possess potent antioxidant
activity in a rat brain homogenate model. Bioassay-guided isolation of the active compounds …
activity in a rat brain homogenate model. Bioassay-guided isolation of the active compounds …
[HTML][HTML] Mechanically stable solvent-free lipid bilayers in nano-and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels
…, M Yoshida, K Arata, T Ohori, K Ishibashi, M Kato… - Scientific Reports, 2017 - nature.com
The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell membrane.
The reconstitution of ion channel proteins in artificially formed BLMs represents a well-…
The reconstitution of ion channel proteins in artificially formed BLMs represents a well-…
[HTML][HTML] Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors
M Pan, C Zorbas, M Sugaya, K Ishiguro, M Kato… - Nature …, 2022 - nature.com
Ribosome biogenesis is an energetically expensive program that is dictated by nutrient
availability. Here we report that nutrient deprivation severely impairs precursor ribosomal RNA (…
availability. Here we report that nutrient deprivation severely impairs precursor ribosomal RNA (…
[HTML][HTML] Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells
H Hosokawa, T Tanaka, Y Endo, M Kato… - Nature …, 2016 - nature.com
Th2 cells produce Th2 cytokines such as IL-4, IL-5 and IL-13, but repress Th1 cytokine IFNγ.
Recent studies have revealed various distinct memory-type Th2 cell subsets, one of which …
Recent studies have revealed various distinct memory-type Th2 cell subsets, one of which …
Advances in artificial cell membrane systems as a platform for reconstituting ion channels
M Komiya, M Kato, D Tadaki, T Ma… - The Chemical …, 2020 - Wiley Online Library
An artificial cell membrane that is composed of bilayer lipid membranes (BLMs) with
transmembrane proteins incorporated within them represents a well‐defined system for the analysis …
transmembrane proteins incorporated within them represents a well‐defined system for the analysis …
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression
H Hosokawa, T Tanaka, M Kato… - Proceedings of the …, 2013 - National Acad Sciences
GATA-binding protein 3 (Gata3) controls the differentiation of naive CD4 T cells into T helper
2 (Th2) cells by induction of chromatin remodeling of the Th2 cytokine gene loci, direct …
2 (Th2) cells by induction of chromatin remodeling of the Th2 cytokine gene loci, direct …
[HTML][HTML] Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells
H Hosokawa, M Kato, H Tohyama, Y Tamaki… - Journal of Biological …, 2015 - ASBMB
Gata3 acts as a master regulator for T helper 2 (Th2) cell differentiation by inducing chromatin
remodeling of the Th2 cytokine loci, accelerating Th2 cell proliferation, and repressing Th1 …
remodeling of the Th2 cytokine loci, accelerating Th2 cell proliferation, and repressing Th1 …
[HTML][HTML] Recombinant human soluble thrombomodulin administration improves sepsis-induced disseminated intravascular coagulation and mortality: a retrospective …
T Kato, T Sakai, M Kato, M Hagihara, T Hasegawa… - Thrombosis …, 2013 - Springer
Background Early treatment of disseminated intravascular coagulation (DIC) can be
associated with improved patient outcomes. The Japanese Ministry of Health and Welfare (JMHW) …
associated with improved patient outcomes. The Japanese Ministry of Health and Welfare (JMHW) …
Comparison of the effects of cilnidipine and amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats
…, T Hattori, T Murase, M Ohtake, M Kato… - Journal of …, 2012 - journals.lww.com
Objective: The L/N-type calcium channel blocker (CCB) cilnidipine suppresses sympathetic
nerve activity and has a superior renoprotective effect compared with L-type CCBs such as …
nerve activity and has a superior renoprotective effect compared with L-type CCBs such as …