User profiles for Mikiyasu Sakanaka
Mikiyasu SakanakaKyoto University Verified email at kyoto-u.ac.jp Cited by 1608 |
[HTML][HTML] Varied Pathways of Infant Gut-Associated Bifidobacterium to Assimilate Human Milk Oligosaccharides: Prevalence of the Gene Set and Its Correlation with …
M Sakanaka, A Gotoh, K Yoshida, T Odamaki… - Nutrients, 2019 - mdpi.com
The infant’s gut microbiome is generally rich in the Bifidobacterium genus. The mother’s milk
contains natural prebiotics, called human milk oligosaccharides (HMOs), as the third most …
contains natural prebiotics, called human milk oligosaccharides (HMOs), as the third most …
[HTML][HTML] Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut
MF Laursen, M Sakanaka, N von Burg, U Mörbe… - Nature …, 2021 - nature.com
Breastfeeding profoundly shapes the infant gut microbiota, which is critical for early life immune
development, and the gut microbiota can impact host physiology in various ways, such …
development, and the gut microbiota can impact host physiology in various ways, such …
[HTML][HTML] Enzymatic Adaptation of Bifidobacterium bifidum to Host Glycans, Viewed from Glycoside Hydrolyases and Carbohydrate-Binding Modules
Certain species of the genus Bifidobacterium represent human symbionts. Many studies
have shown that the establishment of symbiosis with such bifidobacterial species confers …
have shown that the establishment of symbiosis with such bifidobacterial species confers …
Evolution of milk oligosaccharides: Origin and selectivity of the ratio of milk oligosaccharides to lactose among mammals
T Urashima, T Katayama, M Sakanaka… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Background The carbohydrate fraction of mammalian milk is constituted of lactose and
oligosaccharides, most of which contain a lactose unit at their reducing ends. Although lactose is …
oligosaccharides, most of which contain a lactose unit at their reducing ends. Although lactose is …
[HTML][HTML] Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
The early life human gut microbiota exerts life-long health effects on the host, but the
mechanisms underpinning its assembly remain elusive. Particularly, the early colonization of …
mechanisms underpinning its assembly remain elusive. Particularly, the early colonization of …
[HTML][HTML] Sharing of human milk oligosaccharides degradants within bifidobacterial communities in faecal cultures supplemented with Bifidobacterium bifidum
Gut microbiota of breast-fed infants are generally rich in bifidobacteria. Recent studies show
that infant gut-associated bifidobacteria can assimilate human milk oligosaccharides (HMOs…
that infant gut-associated bifidobacteria can assimilate human milk oligosaccharides (HMOs…
Priority effects shape the structure of infant-type Bifidobacterium communities on human milk oligosaccharides
Bifidobacteria are among the first colonizers of the infant gut, and human milk oligosaccharides
(HMOs) in breastmilk are instrumental for the formation of a bifidobacteria-rich microbiota…
(HMOs) in breastmilk are instrumental for the formation of a bifidobacteria-rich microbiota…
Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis
M Sakanaka, ME Hansen, A Gotoh, T Katoh… - Science …, 2019 - science.org
The human gut microbiota established during infancy has persistent effects on health. In vitro
studies have suggested that human milk oligosaccharides (HMOs) in breast milk promote …
studies have suggested that human milk oligosaccharides (HMOs) in breast milk promote …
A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem
…, MN Ojima, H Takada, M Sakanaka… - Nature Chemical …, 2023 - nature.com
Mucinolytic bacteria modulate host–microbiota symbiosis and dysbiosis through their ability
to degrade mucin O-glycans. However, how and to what extent bacterial enzymes are …
to degrade mucin O-glycans. However, how and to what extent bacterial enzymes are …
[PDF][PDF] Molecular insight into evolution of symbiosis between breast-fed infants and a member of the human gut microbiome Bifidobacterium longum
C Yamada, A Gotoh, M Sakanaka, M Hattie… - Cell chemical …, 2017 - cell.com
Breast-fed infants generally have a bifidobacteria-rich microbiota with recent studies indicating
that human milk oligosaccharides (HMOs) selectively promote bifidobacterial growth. …
that human milk oligosaccharides (HMOs) selectively promote bifidobacterial growth. …