Developmental function and state transitions of a gene expression oscillator in Caenorhabditis elegans

MWM Meeuse, YP Hauser… - Molecular Systems …, 2020 - embopress.org
Gene expression oscillators can structure biological events temporally and spatially. Different
biological functions benefit from distinct oscillator properties. Thus, finite developmental …

C. elegans molting requires rhythmic accumulation of the Grainyhead/LSF transcription factor GRH‐1

MWM Meeuse, YP Hauser, S Nahar, AAT Smith… - The EMBO …, 2023 - embopress.org
C. elegans develops through four larval stages that are rhythmically terminated by molts,
that is, the synthesis and shedding of a cuticular exoskeleton. Each larval cycle involves …

The BLMP-1 transcription factor promotes oscillatory gene expression to achieve timely molting

YP Hauser, MWM Meeuse, D Gaidatzis, H Großhans - bioRxiv, 2021 - biorxiv.org
Gene expression oscillators can coordinate developmental events in space and time. In C.
elegans, a gene expression oscillator directs rhythmic accumulation of ∼25% of the …

The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting

MWM Meeuse, S Nahar, K Braun, H Großhans - bioRxiv, 2022 - biorxiv.org
Molting, that is, the synthesis and shedding of a cuticular exoskeleton, is a defining characteristic
of ecdysozoa. In nematodes such as C. elegans, molts rhythmically terminate each of …

[PDF][PDF] State transitions of a developmental oscillator

MWM Meeuse, YP Hauser, G Hendriks, J Eglinger… - Biorxiv, 2020 - researchgate.net
Milou Meeuse and Yannick Hauser analyzed RNA sequencing data. Milou Meeuse performed
… Helge Großhans, Milou Meeuse and Yannick Hauser conceived the project and wrote the …

Developmental function and state transitions of a gene expression oscillator in C. elegans

MWM Meeuse, YP Hauser, GJ Hendriks, J Eglinger… - bioRxiv, 2019 - biorxiv.org
Milou Meeuse and Yannick Hauser analyzed RNA sequencing data. Milou Meeuse performed
… Helge Großhans, Milou Meeuse and Yannick Hauser conceived the project and wrote the …

Functional dissection of a gene expression oscillator in C. elegans

MWM Meeuse - 2021 - edoc.unibas.ch
Gene expression oscillations control diverse biological processes. One such example of
gene expression oscillations, are those found for thousands of genes during C. elegans larval …

Characterization of a developmental oscillator in C. elegans

YP Hauser - 2021 - edoc.unibas.ch
Milou Meeuse and Yannick Hauser analyzed RNA sequencing data. Milou Meeuse performed
… Helge Großhans, Milou Meeuse and Yannick Hauser conceived the project and wrote the …

[HTML][HTML] An nhr-85:: GFP:: AID*:: 3xFLAG knock-in allele for investigation of molting and oscillatory gene regulation

KM Myles, JC Clancy, LC Johnson, G Ashley… - Micropublication …, 2023 - ncbi.nlm.nih.gov
C. elegans NHR-85 is a poorly characterized nuclear hormone receptor transcription factor
with an emerging role in regulating microRNA expression to control developmental timing. …

Nuclear hormone receptor regulation of microRNAs controls developmental progression

A Bethke, N Fielenbach, Z Wang, DJ Mangelsdorf… - Science, 2009 - science.org
In response to small-molecule signals such as retinoids or steroids, nuclear receptors activate
gene expression to regulate development in different tissues. MicroRNAs turn off target …