[PDF][PDF] CD10+ GPR77+ cancer-associated fibroblasts promote cancer formation and chemoresistance by sustaining cancer stemness
S Su, J Chen, H Yao, J Liu, S Yu, L Lao, M Wang… - Cell, 2018 - cell.com
Carcinoma-associated fibroblasts (CAFs) are abundant and heterogeneous stromal cells in
tumor microenvironment that are critically involved in cancer progression. Here, we …
tumor microenvironment that are critically involved in cancer progression. Here, we …
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and …
Our understanding of Alzheimer’s disease (AD) pathophysiology remains incomplete. Here
we used quantitative mass spectrometry and coexpression network analysis to conduct the …
we used quantitative mass spectrometry and coexpression network analysis to conduct the …
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell …
I Dmitriev, V Krasnykh, CR Miller, M Wang… - Journal of …, 1998 - Am Soc Microbiol
Recombinant adenoviruses (Ad) have become the vector system of choice for a variety of
gene therapy applications. However, the utility of Ad vectors is limited due to the low efficiency …
gene therapy applications. However, the utility of Ad vectors is limited due to the low efficiency …
[PDF][PDF] Integrative proteomic characterization of human lung adenocarcinoma
Genomic studies of lung adenocarcinoma (LUAD) have advanced our understanding of the
disease's biology and accelerated targeted therapy. However, the proteomic characteristics …
disease's biology and accelerated targeted therapy. However, the proteomic characteristics …
Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts
E Song, N Ouyang, M Hörbelt, B Antus, M Wang… - Cellular …, 2000 - Elsevier
Activated macrophages regulate fibrogenesis by providing cytokines and growth factors that
modulate the proliferation and collagen synthesis of fibroblasts. However, macrophages can …
modulate the proliferation and collagen synthesis of fibroblasts. However, macrophages can …
Transformer-based unsupervised contrastive learning for histopathological image classification
A large-scale and well-annotated dataset is a key factor for the success of deep learning in
medical image analysis. However, assembling such large annotations is very challenging, …
medical image analysis. However, assembling such large annotations is very challenging, …
[HTML][HTML] Solvent-free microwave synthesis of ultra-small Ru-Mo2C@CNT with strong metal-support interaction for industrial hydrogen evolution
X Wu, Z Wang, D Zhang, Y Qin, M Wang, Y Han… - Nature …, 2021 - nature.com
Exploring a simple, fast, solvent-free synthetic method for large-scale preparation of cheap,
highly active electrocatalysts for industrial hydrogen evolution reaction is one of the most …
highly active electrocatalysts for industrial hydrogen evolution reaction is one of the most …
[PDF][PDF] Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
The impact of apolipoprotein E ε4 (APOE4), the strongest genetic risk factor for Alzheimer's
disease (AD), on human brain cellular function remains unclear. Here, we investigated the …
disease (AD), on human brain cellular function remains unclear. Here, we investigated the …
The paraventricular thalamus controls a central amygdala fear circuit
Appropriate responses to an imminent threat brace us for adversities. The ability to sense
and predict threatening or stressful events is essential for such adaptive behaviour. In the …
and predict threatening or stressful events is essential for such adaptive behaviour. In the …
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease
Innate immunity is associated with Alzheimer’s disease 1 , but the influence of immune
activation on the production of amyloid-β is unknown 2 , 3 . Here we identify interferon-induced …
activation on the production of amyloid-β is unknown 2 , 3 . Here we identify interferon-induced …