Transitions between epithelial and mesenchymal phenotypes – the epithelial to mesenchymal
transition (EMT) and its reverse the mesenchymal to epithelial transition (MET) – are …

Forward and backward transitions between epithelial and mesenchymal phenotypes play
crucial roles in embryonic development and tissue repair. Aberrantly regulated transitions are …

The effects of autologous cytokine-induced killer (CIK) (CD3 + CD56 + ) cells together with
chemotherapy were investigated in patients who suffered from advanced gastric cancers (…

Metabolic plasticity enables cancer cells to switch their metabolism phenotypes between
glycolysis and oxidative phosphorylation (OXPHOS) during tumorigenesis and metastasis. …

Abnormal metabolism is a hallmark of cancer, yet its regulation remains poorly understood.
Cancer cells were considered to utilize primarily glycolysis for ATP production, referred to as …

Here we report the crystal structure of hemagglutinin (HA) from influenza B/Hong Kong/8/73
(B/HK) virus determined to 2.8 Å. At a sequence identity of ∼25% to influenza A virus HAs, …

Here we report an orientation-dependent statistical all-atom potential derived from side-chain
packing, named OPUS-PSP. It features a basis set of 19 rigid-body blocks extracted from …

Epithelial cells undergoing epithelial-to-mesenchymal transitions have often been shown to
behave as cancer stem cells, but the precise molecular connection remains elusive. At the …

Notch signaling pathway mediates cell-fate determination during embryonic development,
wound healing, and tumorigenesis. This pathway is activated when the ligand Delta or the …

One of the most important roles of cells is performing their cellular tasks properly for survival.
Cells usually achieve robust functionality, for example, cell-fate decision-making and signal …