Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …

DNA repair capacity is central in maintaining normal cellular functions. Variants of several
DNA repair genes,including the nucleotide excision repair gene XPD, have been described …

Catecholamines released by sympathetic nerves can activate adrenergic receptors present
on nearly every cell type, including myeloid-derived suppressor cells (MDSCs). Using in vitro …

An immune response must be tightly controlled so that it will be commensurate with the level
of response needed to protect the organism without damaging normal tissue. The roles of …

Background Goat populations that are characterized within the AdaptMap project cover a
large part of the worldwide distribution of this species and provide the opportunity to assess …

Primary and secondary lymphoid organs are heavily innervated by the autonomic nervous
system. Norepinephrine, the primary neurotransmitter secreted by post-ganglionic …

Metabolic dysfunction and exhaustion in tumor-infiltrating T cells have been linked to
ineffectual antitumor immunity and the failure of immune checkpoint inhibitor therapy. We report …

The abscopal effect following ionizing radiation therapy (RT) is considered to be a rare event.
This effect does occur more frequently when combined with other therapies, including …

Low phosphate (Pi) availability limits crop growth and yield in acid soils. Although root-associated
acid phosphatases (APases) play an important role in extracellular organic …

Ethnopharmacological relevance Ophiopogonis Radix (Maidong in Chinese), the root of
Ophiopogon japonicus, is widely used in local medicines of China, Japan and some south-…