Allogeneic stem cell transplantation (alloSCT) of homozygous CCR5 Δ32 stem cells once
resulted in the cure of human immunodeficiency virus (HIV) infection. We have recently …

Purpose. Renal impairment is a common complication after liver transplantation (LT). While
BK polyomavirus (BKV) has been linked to renal failure in kidney transplant recipients, …

Herpes simplex virus (HSV) is a leading cause of blindness and viral encephalitis in the
developed world. Upon reactivation from sensory neurons, HSV returns via axonal transport to …

The increasing incidence of acyclovir (ACV) and multidrug-resistant strains in patients with
corneal HSV-1 infections leading to Herpetic Stromal Keratitis (HSK) is a major health …

After the start of antiretroviral therapy (ART), plasma HIV-RNA levels should fall below the
limit of detection (LOD) within 24 weeks. Hence, the prolonged decline of HIV-RNA after ART …

Regulatory T cells (Tregs) play an important role in the pathogenesis of HIV-1 infection and
they frequently express the chemokine receptor CCR5. We therefore investigated whether …

Purpose: The increasing incidence of antiviral drug-resistant strains in patients with ocular
HSV-1 infection is a major health problem that may lead to blindness. The present study was …

Background Herpes simplex viruses (HSV) cause ubiquitous human infections. For vaccine
development, knowledge concerning correlates of protection is essential. Therefore, we …

Background In approximately 10% of newly diagnosed individuals in Europe, HIV-1 variants
harboring transmitted drug resistance mutations (TDRM) are detected. For some TDRM it …

Despite the availability of antiviral chemotherapy, herpes simplex virus type 1 (HSV-1) and
type 2 (HSV-2) infections remain a severe global health problem. Of particular concern is the …