Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis

…, TOAR Missotten, M Velthoven… - Human molecular …, 2018 - academic.oup.com
Birdshot Uveitis (Birdshot) is a rare eye condition that affects HLA-A29-positive individuals
and could be considered a prototypic member of the recently proposed ‘MHC-I (major …

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

…, MEJ van Velthoven… - Proceedings of the …, 2016 - National Acad Sciences
Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal
diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in …

Recent developments in optical coherence tomography for imaging the retina

MEJ van Velthoven, DJ Faber, FD Verbraak… - Progress in retinal and …, 2007 - Elsevier
Optical coherence tomography (OCT) was introduced in ophthalmology a decade ago.
Within a few years in vivo imaging of the healthy retina and optic nerve head and of retinal …

[HTML][HTML] Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy

…, RPJ Michels, MEJ van Velthoven… - … & visual science, 2009 - iovs.arvojournals.org
purpose. To determine whether type 1 diabetes preferentially affects the inner retinal layers
by comparing the thickness of six retinal layers in type 1 diabetic patients who have no or …

[HTML][HTML] Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes

…, RPJ Michels, MEJ van Velthoven… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: To determine which retinal layers are most affected by diabetes and contribute to
thinning of the inner retina and to investigate the relationship between retinal layer thickness (…

Influence of cataract on optical coherence tomography image quality and retinal thickness

MEJ van Velthoven, MH van der Linden… - British Journal of …, 2006 - bjo.bmj.com
Background: As optical coherence tomography (OCT) is widely used for diagnosis and
monitoring of ocular pathology, especially in the elderly people, the influence of cataract on …

Decreased optical coherence tomography-measured pericentral retinal thickness in patients with diabetes mellitus type 1 with minimal diabetic retinopathy

C Biallosterski, MEJ Van Velthoven… - British journal of …, 2007 - bjo.bmj.com
Aim: A comparison of retinal thickness (RT) measurements with optical coherence
tomography (OCT) in patients with type 1 diabetes mellitus (DM) and no or minimal diabetic …

[HTML][HTML] Safety and efficacy of adalimumab in patients with noninfectious uveitis in an ongoing open-label study: VISUAL III

…, S Pathai, A Camez, A Schlaen, MEJ van Velthoven… - Ophthalmology, 2018 - Elsevier
Purpose To evaluate safety and efficacy of adalimumab in patients with noninfectious
intermediate, posterior, or panuveitis. Design Phase 3, open-label, multicenter clinical trial …

Evaluation of central serous retinopathy with en face optical coherence tomography

MEJ van Velthoven, FD Verbraak, PM Garcia… - British Journal of …, 2005 - bjo.bmj.com
Background: The diagnosis of idiopathic central serous retinopathy (CSR) is usually based
on biomicroscopy and fluorescein angiography (FA). The optical coherence tomography (…

Perigranuloma localization and abnormal maturation of B cells: emerging key players in sarcoidosis?

…, PL Van Daele, ME Van Velthoven… - American journal of …, 2013 - atsjournals.org
Rationale: Recent observations of abnormal immunoglobulin responses and case reports
describing successful B-cell ablative therapy suggest involvement of B cells in the …