Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Neuroepithelial (NE) organoids with dorsal–ventral patterning provide a useful three‐dimensional
(3D) in vitro model to interrogate neural tube formation during early development of …

The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction,
but many details of mechanotransductive signal integration remain elusive due to the …

The extracellular matrix is an important regulator of cell function. Environmental cues existing
in the cellular microenvironment, such as ligand distribution and tissue geometry, have …

In the event of disease or injury, restoration of the native organization of cells and extracellular
matrix is crucial for regaining tissue functionality. In the cornea, a highly organized …

The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction,
but many details of mechanotransductive signal integration remain elusive due to the …

Fibroblasts maintain the ECM properties in the tissues and have the capability to shift its own
phenotype to Myofibroblastic. The latter is normally related to pathological condition. The …

Fibroblasts are one of the most widespread cell type throughout human organism and their
activation can be triggered by both biochemical cues1 and mechanotransductive cues, which …

Building accurate knowledge of the identity, the geographic distribution and the evolution of
species is essential for the sustainable development of humanity, as well as for biodiversity …

The concept of sustainability is multidimensional and includes institutional, social, cultural,
environmental, and economic dimensions. It shows the extent to which humans and the …